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Title:
AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS
Document Type and Number:
WIPO Patent Application WO/2010/137349
Kind Code:
A1
Abstract:
Disclosed is a compound which enhances the activity of neurotrophic factors and exerts a protective action on nerve cells. Specifically disclosed is a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof. In the formula, Z represents N or C-R2; X represents N-R3, O or S; Y represents C-R4 or N; R1 represents a hydrogen atom, an optionally substituted non-cyclic hydrocarbon group or an optionally substituted cyclic group; R2 represents a hydrogen atom, an optionally substituted non-cyclic hydrocarbon group or an optionally substituted cyclic group; R3 represents a hydrogen atom or a substituent; R4 represents a hydrogen atom or a substituent; ring A represents an optionally substituted benzene ring; and ring B represents an optionally substituted benzene ring.

Inventors:
ISHIKAWA JUNICHI (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
Application Number:
PCT/JP2010/003622
Publication Date:
December 02, 2010
Filing Date:
May 28, 2010
Export Citation:
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Assignee:
SUMITOMO CHEMICAL CO (JP)
ISHIKAWA JUNICHI (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
International Classes:
C07D405/14; A61K31/4184; A61K31/423; A61K31/428; A61K31/4439; A61K31/454; A61P1/02; A61P1/04; A61P3/10; A61P7/02; A61P7/04; A61P9/08; A61P9/10; A61P13/12; A61P19/02; A61P19/08; A61P19/10; A61P21/02; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P27/16; A61P29/00; A61P43/00; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D417/14
Domestic Patent References:
WO2008073451A22008-06-19
WO2007115408A12007-10-18
WO2001000213A12001-01-04
WO2008153701A12008-12-18
WO2005082901A12005-09-09
WO2003053344A22003-07-03
Foreign References:
JP2002544199A2002-12-24
US20090156613A12009-06-18
JP2010047517A2010-03-04
JPH0881464A1996-03-26
JP2007282502A2007-11-01
JP2007282501A2007-11-01
EP0468470A11992-01-29
DE19920936A12000-11-09
JPH04308580A1992-10-30
Other References:
See also references of EP 2436683A4
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Attorney, Agent or Firm:
Shinjyu Global IP (JP)
fresh green -- a global IP patent business corporation (JP)
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