Title:
AGENT FOR TREATMENT OR PREVENTION OF DISEASES ASSOCIATED WITH ACTIVITY OF NEUROTROPHIC FACTORS
Document Type and Number:
WIPO Patent Application WO/2010/137349
Kind Code:
A1
Abstract:
Disclosed is a compound which enhances the activity of neurotrophic factors and exerts a protective action on nerve cells. Specifically disclosed is a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof.
In the formula, Z represents N or C-R2; X represents N-R3, O or S; Y represents C-R4 or N; R1 represents a hydrogen atom, an optionally substituted non-cyclic hydrocarbon group or an optionally substituted cyclic group; R2 represents a hydrogen atom, an optionally substituted non-cyclic hydrocarbon group or an optionally substituted cyclic group; R3 represents a hydrogen atom or a substituent; R4 represents a hydrogen atom or a substituent; ring A represents an optionally substituted benzene ring; and ring B represents an optionally substituted benzene ring.
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Inventors:
ISHIKAWA JUNICHI (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
Application Number:
PCT/JP2010/003622
Publication Date:
December 02, 2010
Filing Date:
May 28, 2010
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
ISHIKAWA JUNICHI (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
ISHIKAWA JUNICHI (JP)
SAITO KOICHI (JP)
OHE NORIHISA (JP)
KOBAYASHI KENTARO (JP)
International Classes:
C07D405/14; A61K31/4184; A61K31/423; A61K31/428; A61K31/4439; A61K31/454; A61P1/02; A61P1/04; A61P3/10; A61P7/02; A61P7/04; A61P9/08; A61P9/10; A61P13/12; A61P19/02; A61P19/08; A61P19/10; A61P21/02; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P27/16; A61P29/00; A61P43/00; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D417/14
Domestic Patent References:
WO2008073451A2 | 2008-06-19 | |||
WO2007115408A1 | 2007-10-18 | |||
WO2001000213A1 | 2001-01-04 | |||
WO2008153701A1 | 2008-12-18 | |||
WO2005082901A1 | 2005-09-09 | |||
WO2003053344A2 | 2003-07-03 |
Foreign References:
JP2002544199A | 2002-12-24 | |||
US20090156613A1 | 2009-06-18 | |||
JP2010047517A | 2010-03-04 | |||
JPH0881464A | 1996-03-26 | |||
JP2007282502A | 2007-11-01 | |||
JP2007282501A | 2007-11-01 | |||
EP0468470A1 | 1992-01-29 | |||
DE19920936A1 | 2000-11-09 | |||
JPH04308580A | 1992-10-30 |
Other References:
See also references of EP 2436683A4
NATURE, vol. 322, 1986, pages 552 - 555
THE JOURNAL OF THE AMERICAN SOCIETY FOR EXPERIMENTAL NEUROTHERAPEUTICS, vol. 2, 2005, pages 120 - 128
ANNUAL REVIEW OF NEUROSCIENCE, vol. 24, 2001, pages 1217 - 1281
BRAIN RESEARCH REVIEWS, vol. 30, 1999, pages 176 - 188
PROGRESS IN BRAIN RESEARCH, vol. 146, 2004, pages 387 - 401
CURRENT MEDICINE JAPAN, vol. 54, no. 7, 1999, pages 88 - 94
"From the hyperacute phase to prevention", vol. 1, 2006, article "Studies on Intervention Periods for Stroke", pages: 649 - 654
ZHURNAL OBSHCHEI KHIMII, vol. 32, no. 5, 1962, pages 1581 - 86
ENGL. TRANSL. VER., pages 1565 - 1569
SYNTHESIS, 2003, pages 1683 - 1692
SYNTHESIS, 2008, pages 387 - 394
JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 9, 1988, pages 1778 - 85
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 200412, no. 1, pages 17 - 21
SYNTHETIC COMMUNICATIONS, vol. 28, no. 22, 1998, pages 4123 - 4135
KIYOSHI TOMIOKA: "Strategic Applications of Named Reactions in Organic Synthesis", 15 August 2006, KAGAKU DOJIN, pages: 258 - 259,310-
NATURE, vol. 322, 1986, pages 552 - 555
THE JOURNAL OF THE AMERICAN SOCIETY FOR EXPERIMENTAL NEUROTHERAPEUTICS, vol. 2, 2005, pages 120 - 128
ANNUAL REVIEW OF NEUROSCIENCE, vol. 24, 2001, pages 1217 - 1281
BRAIN RESEARCH REVIEWS, vol. 30, 1999, pages 176 - 188
PROGRESS IN BRAIN RESEARCH, vol. 146, 2004, pages 387 - 401
CURRENT MEDICINE JAPAN, vol. 54, no. 7, 1999, pages 88 - 94
"From the hyperacute phase to prevention", vol. 1, 2006, article "Studies on Intervention Periods for Stroke", pages: 649 - 654
ZHURNAL OBSHCHEI KHIMII, vol. 32, no. 5, 1962, pages 1581 - 86
ENGL. TRANSL. VER., pages 1565 - 1569
SYNTHESIS, 2003, pages 1683 - 1692
SYNTHESIS, 2008, pages 387 - 394
JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 9, 1988, pages 1778 - 85
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 200412, no. 1, pages 17 - 21
SYNTHETIC COMMUNICATIONS, vol. 28, no. 22, 1998, pages 4123 - 4135
KIYOSHI TOMIOKA: "Strategic Applications of Named Reactions in Organic Synthesis", 15 August 2006, KAGAKU DOJIN, pages: 258 - 259,310-
Attorney, Agent or Firm:
Shinjyu Global IP (JP)
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fresh green -- a global IP patent business corporation (JP)
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