Title:
AGENT FOR TREATMENT OR PREVENTION OF HTLV-1-ASSOCIATED MYELOPATHY (HAM), AND HAM TREATMENT METHOD
Document Type and Number:
WIPO Patent Application WO/2020/017629
Kind Code:
A1
Abstract:
The present invention provides: an agent for the treatment or prevention of HTLV-1-associated myelopathy (HAM), the agent containing an RGMa inhibitor; and a HAM treatment method including the administration of a pharmacologically effective amount of an RGMa inhibitor to an HTLV-1-associated myelopathy (HAM) patient in need of the agent.
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Inventors:
UCHIMARU KAORU (JP)
YAMAGISHI MAKOTO (JP)
ISHIZAKI IZUMI (JP)
YAMANO YOSHIHISA (JP)
YAMAGISHI MAKOTO (JP)
ISHIZAKI IZUMI (JP)
YAMANO YOSHIHISA (JP)
Application Number:
PCT/JP2019/028431
Publication Date:
January 23, 2020
Filing Date:
July 19, 2019
Export Citation:
Assignee:
UNIV TOKYO (JP)
UNIV SCHOOL ST MARIANNA MEDICINE (JP)
UNIV SCHOOL ST MARIANNA MEDICINE (JP)
International Classes:
A61K45/00; A61K39/395; A61P25/00; A61P31/12; A61P43/00
Domestic Patent References:
| WO2017210278A1 | 2017-12-07 | |||
| WO2016175236A1 | 2016-11-03 | |||
| WO2005087268A1 | 2005-09-22 | |||
| WO2014007303A1 | 2014-01-09 | |||
| WO2011071059A1 | 2011-06-16 | |||
| WO2016175236A1 | 2016-11-03 |
Foreign References:
| JP2006516594A | 2006-07-06 | |||
| JP2013119531A | 2013-06-17 | |||
| JP2014138599A | 2014-07-31 | |||
| JP2016175897A | 2016-10-06 | |||
| JP2017526930W | ||||
| JP2010100578A | 2010-05-06 | |||
| JP2015508061W |
Other References:
N ENGL J MED, vol. 378, 2018, pages 529 - 538
YAMASHITA, T.MUELLER, B.K.HATA, K.: "Neogenin and repulsive guidance molecule signaling in the central nervous system", CURR. OPIN. NEUROBIOL., vol. 17, 2007, pages 29 - 34, XP005931698, DOI: 10.1016/j.conb.2006.12.001
KABAT ET AL.: "Sequences of Proteins of Immunological Interest", 1987, US DEPARTMENT OF HEALTH AND HUMAN SERVICES, NIH
See also references of EP 3824907A4
YAMASHITA, T.MUELLER, B.K.HATA, K.: "Neogenin and repulsive guidance molecule signaling in the central nervous system", CURR. OPIN. NEUROBIOL., vol. 17, 2007, pages 29 - 34, XP005931698, DOI: 10.1016/j.conb.2006.12.001
KABAT ET AL.: "Sequences of Proteins of Immunological Interest", 1987, US DEPARTMENT OF HEALTH AND HUMAN SERVICES, NIH
See also references of EP 3824907A4
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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