Title:
AIE LUMINOGENS FOR VISUALIZATION AND TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2016/206615
Kind Code:
A1
Abstract:
The present subject matter relates to AIE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.
Inventors:
TANG BENZHONG (CN)
ZHAO ENGUI (CN)
GUI CHEN (CN)
JIANG MEIJUAN (CN)
DENG HAIQIN (CN)
LEUNG WAI TUNG (CN)
WANG ZHIMING (CN)
ZHAO YUEYUE (CN)
KWOK TSZ KIN (CN)
VIGLIANTI LUCIA (IT)
XIE NI (CN)
ZHAO ENGUI (CN)
GUI CHEN (CN)
JIANG MEIJUAN (CN)
DENG HAIQIN (CN)
LEUNG WAI TUNG (CN)
WANG ZHIMING (CN)
ZHAO YUEYUE (CN)
KWOK TSZ KIN (CN)
VIGLIANTI LUCIA (IT)
XIE NI (CN)
Application Number:
PCT/CN2016/086980
Publication Date:
December 29, 2016
Filing Date:
June 24, 2016
Export Citation:
Assignee:
UNIV HONG KONG SCIENCE & TECH (CN)
International Classes:
C09K11/06; A61K31/44; A61K31/555; A61K41/00; A61K49/00; A61P35/00; C08G65/00
Foreign References:
| CN104974745A | 2015-10-14 | |||
| US20140212359A1 | 2014-07-31 |
Other References:
ERIK FISCHER ET AL.: "Synthesis of New Sulfur Heteroaromatics Isoelectronic with Dibenzo[g,p]chrysene by Photocyclization of Thienyl- and Phenyl-Substituted Ethenes.", JOURNAL OF ORGANIC CHEMISTRY, vol. 61, no. 20, 30 December 1996 (1996-12-30), pages 6997 - 7005, XP002120346
Attorney, Agent or Firm:
TEE&HOWE INTELLECTUAL PROPERTY ATTORNEYS (Yeping10th Floor, Tower D, Minsheng Financial Center,28 Jianguomennei Avenue, Dongcheng District, Beijing 5, CN)
Download PDF:
Previous Patent: LONGWALL MINE CONSTRUCTION METHOD 110
Next Patent: EQUIPMENT SYSTEM FOR NO-ROADWAY NO-COAL-PILLAR RETAINED ROADWAY MINING METHOD
Next Patent: EQUIPMENT SYSTEM FOR NO-ROADWAY NO-COAL-PILLAR RETAINED ROADWAY MINING METHOD