Title:
AKKERMANSIA MUCINIPHILA PROLIFERATION MATERIAL
Document Type and Number:
WIPO Patent Application WO/2019/092896
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel proliferation material which enables the proliferation of Akkermansia muciniphila. An Akkermansia muciniphila proliferation material containing at least one polyphenol component selected from the group consisting of quercetin glycoside, isorhamnetin, cyanidin glucoside, hesperetin, hesperidin, apigenin, chrysin, tangeretin, nobiletin and tannic acid.
Inventors:
ICHISHIMA MUTSUKI (JP)
MORITA HIROTO (JP)
MORITA HIROTO (JP)
Application Number:
PCT/JP2018/009869
Publication Date:
May 16, 2019
Filing Date:
March 14, 2018
Export Citation:
Assignee:
ASAHI GROUP HOLDINGS LTD (JP)
International Classes:
C12N1/38; A23K10/16; A23K20/111; A23K20/121; A23L33/105; A23L33/135; A61K31/7024; A61K31/7048; A61K35/741; A61P3/04; A61P3/10; C12N1/20
Domestic Patent References:
| WO2014175180A1 | 2014-10-30 | |||
| WO2016122889A1 | 2016-08-04 |
Foreign References:
| JP2016503418A | 2016-02-04 |
Other References:
KEMPERMAN, R. A. ET AL.: "Impact of polyphenols from black tea and red wine/grape juice on a gut model microbiome", FOOD RESEARCH INTERNATIONAL, vol. 53, 2013, pages 659 - 669, XP028697101, ISSN: 0963-9969, DOI: doi:10.1016/j.foodres.2013.01.034
ROOPCHAND, D. E. ET AL.: "Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome", DIABETES, vol. 64, no. 8, August 2015 (2015-08-01), pages 2847 - 2858, XP055608406, ISSN: 0012-1797
DERRIEN, M. ET AL.: "Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 54, 2004, pages 1469 - 1476, XP055074486, ISSN: 1466-5026, DOI: doi:10.1099/ijs.0.02873-0
HENNING, S. M. ET AL.: "Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo", ANAEROBE, vol. 43, 7 December 2016 (2016-12-07), pages 56 - 60, XP029902931, ISSN: 1075-9964, DOI: doi:10.1016/j.anaerobe.2016.12.003
RUBERTO, G. ET AL.: "Polyphenol constituents and antioxidant activity of grape pomace extracts from five Sicilian red grape cultivars", FOOD CHEMISTRY, vol. 100, 2007, pages 203 - 210, XP005517186, ISSN: 0308-8146, DOI: doi:10.1016/j.foodchem.2005.09.041
ROOPCHAND, D. E. ET AL.: "Dietary polyphenols promote growth of the gut bacterium Akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome", DIABETES, vol. 64, no. 8, August 2015 (2015-08-01), pages 2847 - 2858, XP055608406, ISSN: 0012-1797
DERRIEN, M. ET AL.: "Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 54, 2004, pages 1469 - 1476, XP055074486, ISSN: 1466-5026, DOI: doi:10.1099/ijs.0.02873-0
HENNING, S. M. ET AL.: "Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo", ANAEROBE, vol. 43, 7 December 2016 (2016-12-07), pages 56 - 60, XP029902931, ISSN: 1075-9964, DOI: doi:10.1016/j.anaerobe.2016.12.003
RUBERTO, G. ET AL.: "Polyphenol constituents and antioxidant activity of grape pomace extracts from five Sicilian red grape cultivars", FOOD CHEMISTRY, vol. 100, 2007, pages 203 - 210, XP005517186, ISSN: 0308-8146, DOI: doi:10.1016/j.foodchem.2005.09.041
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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