Title:
AKT INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2020/156437
Kind Code:
A1
Abstract:
The present invention discloses an AKT inhibitor, and specifically relates to a compound represented by formula I or a pharmaceutically acceptable salt thereof. The present invention further provides a preparation method thereof, and the use thereof in prevention and/or treatment of a disease mediated by AKT protein kinase.
Inventors:
MA CHANGYOU (CN)
TIAN HE (CN)
AN JIE (CN)
ZHAO JIANLIANG (CN)
CHEN DONGHUI (CN)
WU JIAN (CN)
XU DAN (CN)
ZHU CHUNXIA (CN)
TIAN ZHOUSHAN (CN)
TIAN HE (CN)
AN JIE (CN)
ZHAO JIANLIANG (CN)
CHEN DONGHUI (CN)
WU JIAN (CN)
XU DAN (CN)
ZHU CHUNXIA (CN)
TIAN ZHOUSHAN (CN)
Application Number:
PCT/CN2020/073798
Publication Date:
August 06, 2020
Filing Date:
January 22, 2020
Export Citation:
Assignee:
NANJING CHIA TAI TIANQING PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/04; A61K31/519; A61P35/00; C07D475/06; C07D498/04; C07D519/00
Foreign References:
CN1882347A | 2006-12-20 | |||
CN102574852A | 2012-07-11 | |||
CN201910084801A | 2019-01-29 | |||
CN101631778A | 2010-01-20 | |||
CN101578273A | 2009-11-11 | |||
CN101511842A | 2009-08-19 | |||
CN101970415A | 2011-02-09 |
Other References:
DATABASE REGISTRY 4 July 2005 (2005-07-04), ANONYMOUS: "1-Propanone, 2-amino-3-(4-chlorophenyl)-1-[4-(5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-, (2R)-(CA INDEX NAME)", XP055835442, retrieved from STN Database accession no. 853686-96-1
See also references of EP 3919491A4
See also references of EP 3919491A4
Attorney, Agent or Firm:
MERITS & TREE (CN)
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