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Title:
AKT INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2020/156437
Kind Code:
A1
Abstract:
The present invention discloses an AKT inhibitor, and specifically relates to a compound represented by formula I or a pharmaceutically acceptable salt thereof. The present invention further provides a preparation method thereof, and the use thereof in prevention and/or treatment of a disease mediated by AKT protein kinase.

Inventors:
MA CHANGYOU (CN)
TIAN HE (CN)
AN JIE (CN)
ZHAO JIANLIANG (CN)
CHEN DONGHUI (CN)
WU JIAN (CN)
XU DAN (CN)
ZHU CHUNXIA (CN)
TIAN ZHOUSHAN (CN)
Application Number:
PCT/CN2020/073798
Publication Date:
August 06, 2020
Filing Date:
January 22, 2020
Export Citation:
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Assignee:
NANJING CHIA TAI TIANQING PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/04; A61K31/519; A61P35/00; C07D475/06; C07D498/04; C07D519/00
Foreign References:
CN1882347A2006-12-20
CN102574852A2012-07-11
CN201910084801A2019-01-29
CN101631778A2010-01-20
CN101578273A2009-11-11
CN101511842A2009-08-19
CN101970415A2011-02-09
Other References:
DATABASE REGISTRY 4 July 2005 (2005-07-04), ANONYMOUS: "1-Propanone, 2-amino-3-(4-chlorophenyl)-1-[4-(5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-, (2R)-(CA INDEX NAME)", XP055835442, retrieved from STN Database accession no. 853686-96-1
See also references of EP 3919491A4
Attorney, Agent or Firm:
MERITS & TREE (CN)
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