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Title:
ALGORITHM FOR THE AUTOMATIC DETERMINATION OF OPTIMAL PACING INTERVALS
Document Type and Number:
WIPO Patent Application WO2005123178
Kind Code:
A3
Abstract:
Impedance, e.g. sub-threshold impedance, is measured across the heart at selected cardiac cycle times as a measure of chamber expansion or contraction. One embodiment measures impedance over a long AV interval to obtain the minimum impedance, indicative of maximum ventricular expansion, in order to set the AV interval. Another embodiment measures impedance change over a cycle and varies the AV pace interval in a binary search to converge on the AV interval causing maximum impedance change indicative of maximum ventricular output. Another method varies the right ventricle to left ventricle (VV) interval to converge on an impedance maximum indicative of minimum cardiac volume at end systole. Another embodiment varies the VV interval to maximize impedance change. Other methods vary the AA interval to maximize impedance change over the entire cardiac cycle or during the atrial cycle.

Inventors:
BRUNES JOHN E (US)
IGEL DAVID E (US)
RUETER JOHN C (US)
ZLINSKI JODY (US)
CHO YONG KYUN (US)
MONGEON LUC R (US)
STONE HAROLD E (US)
Application Number:
PCT/US2005/018920
Publication Date:
February 09, 2006
Filing Date:
May 26, 2005
Export Citation:
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Assignee:
MEDTRONIC INC (US)
BRUNES JOHN E (US)
IGEL DAVID E (US)
RUETER JOHN C (US)
ZLINSKI JODY (US)
CHO YONG KYUN (US)
MONGEON LUC R (US)
STONE HAROLD E (US)
International Classes:
A61N1/362; A61N1/00; A61N1/365; A61N1/368; A61N1/372
Foreign References:
US20030204212A12003-10-30
EP1350539A12003-10-08
US20030083700A12003-05-01
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