Title:
ALIPHATIC AMINO-SUBSTITUTED DEMETHOXYLATED HYPOCRELLINS AND THEIR SYNTHESIS
Document Type and Number:
WIPO Patent Application WO2002034708
Kind Code:
A3
Abstract:
The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.
Inventors:
ZHANG MANHUA (CN)
XU SHANGJIE (CN)
WU TAO (CN)
CHEN SHEN (CN)
SHEN TAO (CN)
XU SHANGJIE (CN)
WU TAO (CN)
CHEN SHEN (CN)
SHEN TAO (CN)
Application Number:
PCT/IB2001/001993
Publication Date:
March 13, 2003
Filing Date:
October 24, 2001
Export Citation:
Assignee:
ALTACHEM PHARMA LTD (CA)
INST OF PHOTOGRAPHIC CHEMISTRY (CN)
ZHANG MANHUA (CN)
XU SHANGJIE (CN)
WU TAO (CN)
CHEN SHEN (CN)
SHEN TAO (CN)
INST OF PHOTOGRAPHIC CHEMISTRY (CN)
ZHANG MANHUA (CN)
XU SHANGJIE (CN)
WU TAO (CN)
CHEN SHEN (CN)
SHEN TAO (CN)
International Classes:
A61K31/135; A61K31/136; A61K41/00; A61P35/00; C07C213/02; C07C213/10; C07C215/44; C07C225/32; C07D213/38; (IPC1-7): C07C225/32; A61K31/135; C07D213/38; A61P35/00
Other References:
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002213925, Database accession no. 2000:282018
DATABASE WPI Section Ch Week 200066, Derwent World Patents Index; Class B05, AN 2000-673186, XP002213928
DATABASE WPI Section Ch Week 200066, Derwent World Patents Index; Class B05, AN 2000-673186, XP002213928
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