Title:
ALKYLATED C-SUGARS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002072593
Kind Code:
A3
Abstract:
The present invention relates to alkylated C-sugars which are now carbohydrate derivatives based on the "C-Sugar" platform. These alkylated C-sugars are converted from hydrophilic, hydrogen-bonded saccharide derivatives and are very stable, highly soluble and relatively low molecular weight structures. These alkylated C-sugars can serve as effective bioconjugates and pharmaceutical carriers.
Inventors:
SPATOLA ARNO F (US)
TAYLOR K GRANT (US)
BRUNEL FLORENCE (FR)
TAYLOR K GRANT (US)
BRUNEL FLORENCE (FR)
Application Number:
PCT/US2002/007092
Publication Date:
March 13, 2003
Filing Date:
March 11, 2002
Export Citation:
Assignee:
UNIV LOUISVILLE RES FOUND (US)
SPATOLA ARNO F (US)
TAYLOR K GRANT (US)
BRUNEL FLORENCE (FR)
SPATOLA ARNO F (US)
TAYLOR K GRANT (US)
BRUNEL FLORENCE (FR)
International Classes:
C07H5/06; C07H7/00; C07H15/04; (IPC1-7): C07H5/04; C07H5/06
Foreign References:
| US5679769A | 1997-10-21 |
Other References:
HOSOMI, A. ET AL.: "Hihgly stereoselective C-allylation of glycopyranosides with allylsilanes catalyzed by silyl triflate or iodosilane", TETRAHEDRON LETTERS, vol. 25, no. 22, 1984, pages 2383 - 2386, XP002951120
WILLIAMS, R.M. ET AL.: "C-glyosidation of pyridyl thioglycosides", TETRAHEDRON LETTERS, vol. 24, no. 27, 1983, pages 2715 - 2718, XP002951119
WILLIAMS, R.M. ET AL.: "C-glyosidation of pyridyl thioglycosides", TETRAHEDRON LETTERS, vol. 24, no. 27, 1983, pages 2715 - 2718, XP002951119
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