Title:
ALKYNYL MULTI-ARM POLYETHYLENE GLYCOL DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/081832
Kind Code:
A1
Abstract:
The present invention provides an alkynyl multi-arm polyethylene glycol derivative having a structure of a general formula I or general formula X VIII. In the derivative, X1, X2, X3, and X4 are linking groups, F1, F2, F3, and F4 are end groups, the end groups may be the same or may also be different, and are selected from: oxhydryl, carboxyl, ester groups, amine groups, alkynyl or the like, at least one of the end groups is alkynyl, and PEG is the same or different-(CH2CH2O)m-, wherein m is an integer ranging from 3 to 250, and l is an integer greater than or equal to 1. The multi-arm polyethylene glycol has multiple branches, may be loaded with multiple active end groups, and meanwhile may further be loaded with multiple different active end groups, so that the obtained multi-arm polyethylene glycol derivative has a stronger application flexibility and a larger application range, and has a good application prospect in aspects such as organic synthesis, medicine synthesis and medical devices.
Inventors:
LIN MEINA (CN)
CHEN XIAOMENG (CN)
CHEN XIAOMENG (CN)
Application Number:
PCT/CN2014/092738
Publication Date:
June 11, 2015
Filing Date:
December 02, 2014
Export Citation:
Assignee:
JENKEM TECHNOLOGY CO LTD BEIJING (CN)
International Classes:
C08G65/329
Domestic Patent References:
| WO2002040058A2 | 2002-05-23 |
Foreign References:
| CN101549169A | 2009-10-07 | |||
| CN101724144A | 2010-06-09 | |||
| CN102108119A | 2011-06-29 | |||
| US20090324742A1 | 2009-12-31 |
Attorney, Agent or Firm:
SBZL IP LAW OFFICE (CN)
北京商专永信知识产权代理事务所（普通合伙） (CN)
北京商专永信知识产权代理事务所（普通合伙） (CN)
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