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Title:
ALPHA SUBSTITUTED CARBOXYLIC ACID AS PPAR MODULATORS
Document Type and Number:
WIPO Patent Application WO2004092145
Kind Code:
A8
Abstract:
Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R9a, R10, R", R12, R17, ring A, and p are as defined in the specification; pharmaceutical compositions containing effective amounts of said compounds or their salts are useful for treating PPAR, specifically PPAR alpha/y related disorders, such as diabetes, dyslipidemia, obesity and inflammatory disorders.

Inventors:
BAILEY SIMON (US)
HUMPHRIES PAUL STUART (US)
SKALITZKY DONALD JAMES (US)
SU WEI-GUO (US)
ZEHNDER LUKE RAYMOND (US)
Application Number:
IB2004001159W
Publication Date:
May 12, 2005
Filing Date:
April 01, 2004
Export Citation:
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Assignee:
PFIZER INC.
BAILEY, SIMON
HUMPHRIES, PAUL, STUART
SKALITZKY, DONALD, JAMES
SU, WEI-GUO
ZEHNDER, LUKE, RAYMOND
International Classes:
C07C59/125; C07C59/68; C07C61/04; C07C62/34; C07C249/06; C07C271/14; C07C271/16; C07C311/08; C07C311/29; C07C317/22; C07D213/66; C07D249/06; C07D263/32; C07D307/79; C07D401/04; C07D405/06; C07D413/12; C07D413/14; C07D417/14; (IPC1-7): C07D263/32; C07C59/125; C07D401/04; C07D411/12; C07D249/06; C07D213/66; C07C61/04; C07D307/79; C07D413/14; C07D417/14; C07D405/06; C07D413/12
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