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Title:
ALPHA(V)BETA(6) INTEGRIN-BINDING PEPTIDES AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/218569
Kind Code:
A3
Abstract:
The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.

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Inventors:
TANG YNG (US)
SUTCLIFFE JULIE L (US)
Application Number:
PCT/US2017/037303
Publication Date:
February 01, 2018
Filing Date:
June 13, 2017
Export Citation:
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Assignee:
UNIV CALIFORNIA (US)
International Classes:
C07K7/06; A61K38/00; A61K47/60
Domestic Patent References:
WO2015160770A12015-10-22
Foreign References:
US20070037262A12007-02-15
Other References:
DATABASE Uniprot [o] 2 November 2016 (2016-11-02), XP055584258, Database accession no. A0A1B3WS33
Attorney, Agent or Firm:
ROBERTS, Byron N. et al. (US)
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