Title:
AMELIORATING AGENT FOR DETRUSOR HYPERACTIVITY WITH IMPAIRED CONTRACTILITY
Document Type and Number:
WIPO Patent Application WO/2017/022787
Kind Code:
A1
Abstract:
The problem to be solved by the present invention is to provide a method for treating detrusor hyperactivity with impaired contractility. The present invention provides a method for treating detrusor hyperactivity with impaired contractility, which contains 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one, a salt of the compound or a solvate of the compound or the salt as an active ingredient.
Inventors:
HAYASHI YUKIO (JP)
NOMA TAKAHISA (JP)
NOMA TAKAHISA (JP)
Application Number:
PCT/JP2016/072753
Publication Date:
February 09, 2017
Filing Date:
August 03, 2016
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/122; A61P13/10
Foreign References:
| JP2015067565A | 2015-04-13 | |||
| JP2015086212A | 2015-05-07 | |||
| JP2002241271A | 2002-08-28 |
Other References:
SAITO, M. ET AL.: "Effect of cyclohexenonic long-chain fatty alcohol on rat overactive bladder induced by bladder neck obstruction", EUR. J. PHARMACOL., vol. 501, 2004, pages 143 - 149, XP055361861
SHUKO KOKUBUN ET AL.: "Heisoku Boko ni Okeru Joshinkei to Boko Heikatsukin no Shushuku Shogai -Cyclohexenones Yudotai(TAC-302) no Joshinkei Yobo Koka", THE JAPANESE JOURNAL OF UROLOGY, vol. 102, no. 2, 2011, pages 352, XP009509045
NOMIYA, M. ET AL.: "A neurotrophic agent, N- hexacosanol, prevents the development of bladder hyperactivity in a rat model of chronic bladder ischemia", J. UROLOGY, vol. 193, no. 4S, April 2015 (2015-04-01), pages e77, XP029153350
WATANABE, T. ET AL.: "Effects of long- chain fatty alcohol on peripheral nerve conduction and bladder function in diabetic rats", LIFE SCIENCES, vol. 70, 2002, pages 2215 - 2224, XP055362530
SHUKO KOKUBUN ET AL.: "Heisoku Boko ni Okeru Joshinkei to Boko Heikatsukin no Shushuku Shogai -Cyclohexenones Yudotai(TAC-302) no Joshinkei Yobo Koka", THE JAPANESE JOURNAL OF UROLOGY, vol. 102, no. 2, 2011, pages 352, XP009509045
NOMIYA, M. ET AL.: "A neurotrophic agent, N- hexacosanol, prevents the development of bladder hyperactivity in a rat model of chronic bladder ischemia", J. UROLOGY, vol. 193, no. 4S, April 2015 (2015-04-01), pages e77, XP029153350
WATANABE, T. ET AL.: "Effects of long- chain fatty alcohol on peripheral nerve conduction and bladder function in diabetic rats", LIFE SCIENCES, vol. 70, 2002, pages 2215 - 2224, XP055362530
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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