Title:
AMELIORATION OF THE EFFECTS OF FRIEDRIECH'S ATAXIA
Document Type and Number:
WIPO Patent Application WO/2015/026708
Kind Code:
A3
Abstract:
The effects of Friedreich's Ataxia are ameliorated by administering to a patient known or suspected of having the disease with essentially free cis Δ9 fatty acid having from 12 to 24 carbon atoms and a single double bond in a cis configuration at the C9 carbon atom. Dosage regimes and kits are also featured.
Inventors:
WILSON ROBERT B (US)
COTTICELLI M GRAZIA (US)
CRABBE ANDREW M (US)
COTTICELLI M GRAZIA (US)
CRABBE ANDREW M (US)
Application Number:
PCT/US2014/051454
Publication Date:
November 19, 2015
Filing Date:
August 18, 2014
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
International Classes:
A61K31/20; A61K31/201; A61P25/14; C07C57/02
Domestic Patent References:
| WO2007035496A1 | 2007-03-29 |
Foreign References:
| EP2272383A1 | 2011-01-12 | |||
| US20090291092A1 | 2009-11-26 | |||
| US20120040014A1 | 2012-02-16 |
Other References:
NAVARRO, JA: "Altered Lipid Metabolism in a Drosophila Model of Friedreich's Ataxia.", HUMAN MOLECULAR GENETICS., 2010, pages 1 - 13, XP055236237
Attorney, Agent or Firm:
CALDWELL, John, W. et al. (Cira Centre 12th Floor,2929 Arch Stree, Philadelphia PA, US)
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