Title:
AMIDE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2015/147020
Kind Code:
A1
Abstract:
[Problem] To provide a compound useful as an active ingredient of a pharmaceutical composition, e.g., a pharmaceutical composition for the treatment of chronic renal failure and/or diabetic nephropathy. [Solution] The inventors conducted in-depth studies of compounds having an EP4 receptor-antagonizing effect, discovered an amide compound or salt thereof having an EP4 receptor-antagonizing effect, and perfected the present invention. The amide compound or salt thereof has an EP4 receptor-antagonizing effect and can be used as an active ingredient of a pharmaceutical composition for the prevention and/or treatment of various diseases in which EP4 is involved, e.g., chronic renal failure and/or diabetic nephropathy.
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Inventors:
OKUDA TAKAO (JP)
NOZAWA EISUKE (JP)
UGAWA TOHRU (JP)
MIZOGUCHI RYO (JP)
NOZAWA EISUKE (JP)
UGAWA TOHRU (JP)
MIZOGUCHI RYO (JP)
Application Number:
PCT/JP2015/059026
Publication Date:
October 01, 2015
Filing Date:
March 25, 2015
Export Citation:
Assignee:
ASTELLAS PHARMA INC (JP)
International Classes:
C07D401/04; A61K31/4725; A61P3/10; A61P13/12; A61P43/00
Domestic Patent References:
| WO2009139373A1 | 2009-11-19 | |||
| WO2009005076A1 | 2009-01-08 |
Other References:
See also references of EP 3124480A4
Attorney, Agent or Firm:
MORITA, Hiroshi et al. (JP)
Morita 拓 (JP)
Morita 拓 (JP)
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