AMIDE DERIVATIVE AND USE THEREOF

WIPO Patent Application WO/2012/050159

A1

The present invention relates to a novel amide derivative. More specifically, the present invention provides a medicinal agent useful as a prophylactic or therapeutic agent for diseases, which relies on the production of cytokines from T cells, and which comprises an amide derivative or a pharmacologically acceptable salt thereof or a solvate of the derivative or the pharmacologically acceptable salt as an active ingredient. Provided is an amide derivative represented by general formula (I) [wherein each symbol is as defined in the description] or a pharmacologically acceptable salt thereof, or a solvate of the derivative or the pharmacologically acceptable salt.

WO/2001/040185	COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION
WO/2007/110237	AMIDE DERIVATIVES AND THEIR APPLICATION FOR THE TREATMENT OF G PROTEIN RELATED DISEASES
WO/2004/099185	2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS

USHIO, Hiroyuki (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
牛尾　博之 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
HAMADA, Maiko (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
濱田　真以子 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
WATANABE, Masayuki (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
渡辺　雅之 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
NUMATA, Atsushi (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
沼田　敦 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)

JP2011/073532

April 19, 2012

October 13, 2011

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MITSUBISHI TANABE PHARMA CORPORATION (2-6-18, Kitahama Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
田辺三菱製薬株式会社 (〒05 大阪府大阪市中央区北浜二丁目６番１８号 Osaka, 〒5418505, JP)
USHIO, Hiroyuki (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
牛尾　博之 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
HAMADA, Maiko (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
濱田　真以子 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
WATANABE, Masayuki (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)
渡辺　雅之 (〒05 大阪府大阪市中央区北浜二丁目６番１８号　田辺三菱製薬株式会社内 Osaka, 〒5418505, JP)
NUMATA, Atsushi (2-6-18 Kitahama, Chuo-ku, Osaka-sh, Osaka 05, 〒5418505, JP)

C07D401/12; A61K31/443; A61K31/4439; A61K31/4545; A61K31/455; A61K31/5377; A61P19/02; A61P29/00; A61P37/02; A61P43/00; C07D401/14; C07D405/12; C07D405/14; C07D417/12; C07D495/04

TANAKA, Mitsuo et al. (AOYAMA & PARTNERS, IMP Building 3-7, Shiromi 1-chome, Chuo-ku, Osaka-sh, Osaka 01, 〒5400001, JP)

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