Title:
AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS
Document Type and Number:
WIPO Patent Application WO2006012227
Kind Code:
A3
Abstract:
The present invention relates to inhibitors of 11-ß hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor MR, and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-ß hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Inventors:
YAO WENQING (US)
ZHANG COLIN (US)
XU MEIZHONG (US)
ZHUO JINCONG (US)
HE CHUNHONG (US)
METCALF BRIAN (US)
ZHANG COLIN (US)
XU MEIZHONG (US)
ZHUO JINCONG (US)
HE CHUNHONG (US)
METCALF BRIAN (US)
Application Number:
PCT/US2005/022308
Publication Date:
May 04, 2006
Filing Date:
June 23, 2005
Export Citation:
Assignee:
INCYTE CORP (US)
YAO WENQING (US)
ZHANG COLIN (US)
XU MEIZHONG (US)
ZHUO JINCONG (US)
HE CHUNHONG (US)
METCALF BRIAN (US)
YAO WENQING (US)
ZHANG COLIN (US)
XU MEIZHONG (US)
ZHUO JINCONG (US)
HE CHUNHONG (US)
METCALF BRIAN (US)
International Classes:
C07D229/00; A61K31/165; A61K31/395; A61K31/44; A61K31/445; C07C233/58; C07C233/60; C07C233/63; C07C235/40; C07C317/44; C07C323/61; C07D207/14; C07D209/14; C07D211/58; C07D213/30; C07D213/38; C07D213/81; C07D307/22; C07D307/38; C07D309/14; C07D319/20
Domestic Patent References:
| WO2003053915A2 | 2003-07-03 |
Other References:
See also references of EP 1773780A4
Download PDF:
Previous Patent: N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS
Next Patent: FLEXIBLE STORAGE BAG
Next Patent: FLEXIBLE STORAGE BAG