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Title:
AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/153159
Kind Code:
A1
Abstract:
It is intended to provide a novel amine compound represented by the following general formula (I), a pharmaceutically acceptable acid addition salt thereof, a hydrate thereof or a solvate thereof, which has an excellent peripheral blood lymphocyte decreasing action, exhibits excellent immunosuppressive action, antirejection action and the like, and has reduced side effects such as bradycardia. (In the formula, each symbol has the same meaning as in the description.)

Inventors:
KIUCHI, Masatoshi (2-10 Dosho-machi 3-chome, Chuo-ku, Osaka-sh, Osaka 05, 5418505, JP)
城内 正壽 (〒05 大阪府大阪市中央区道修町3丁目2番10号 田辺三菱製薬株式会社内 Osaka, 5418505, JP)
MARUKAWA, Kaoru (2-10 Dosho-machi 3-chome, Chuo-ku, Osaka-sh, Osaka 05, 5418505, JP)
丸川 薫 (〒05 大阪府大阪市中央区道修町3丁目2番10号 田辺三菱製薬株式会社内 Osaka, 5418505, JP)
Application Number:
JP2008/060915
Publication Date:
December 18, 2008
Filing Date:
June 13, 2008
Export Citation:
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Assignee:
MITSUBISHI TANABE PHARMA CORPORATION (2-10, Dosho-machi 3-chome Chuo-ku, Osaka-sh, Osaka 05, 5418505, JP)
田辺三菱製薬株式会社 (〒05 大阪府大阪市中央区道修町3丁目2番10号 Osaka, 5418505, JP)
KIUCHI, Masatoshi (2-10 Dosho-machi 3-chome, Chuo-ku, Osaka-sh, Osaka 05, 5418505, JP)
城内 正壽 (〒05 大阪府大阪市中央区道修町3丁目2番10号 田辺三菱製薬株式会社内 Osaka, 5418505, JP)
MARUKAWA, Kaoru (2-10 Dosho-machi 3-chome, Chuo-ku, Osaka-sh, Osaka 05, 5418505, JP)
International Classes:
C07C217/64; A61K31/137; A61K31/165; A61K31/343; A61K31/36; A61K31/381; A61K31/4453; A61K31/5375; A61K31/661; A61P37/02; A61P37/08; A61P41/00; A61P43/00; C07C255/54; C07C255/59; C07C317/22; C07C323/19; C07C323/32; C07D211/14; C07D295/08; C07D307/79; C07D317/22; C07D317/62; C07D333/16; C07D333/28; C07D333/56; C07F9/09; C07F9/655; C07F9/6553
Domestic Patent References:
WO2007069712A12007-06-21
Foreign References:
JP2007008957A2007-01-18
JP2006524660A2006-11-02
JP2006527231A2006-11-30
Other References:
See also references of EP 2168944A4
None
Attorney, Agent or Firm:
TAKASHIMA, Hajime (Meiji Yasuda Seimei Osaka Midosuji Bldg, 1-1 Fushimimachi 4-chome,Chuo-ku, Osaka-shi, Osaka 44, 5410044, JP)
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