Title:
AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES
Document Type and Number:
WIPO Patent Application WO/2013/161816
Kind Code:
A1
Abstract:
The present invention provides a compound represented by general formula (I) [wherein each symbol is as defined in the description], which has an excellent peripheral blood lymphocyte-reducing activity and is useful for the treatment or prevention of autoimmune diseases, the prevention or inhibition of resistance or acute or chronic rejection of an organ or a tissue against transplantation, the treatment or prevention of graft-versus-host (GvH) disease caused by bone marrow transplantation, or the treatment or prevention of allergic diseases.
Inventors:
HAMADA MAIKO (JP)
TASHIRO KAORU (JP)
SAKASHITA HIROSHI (JP)
KIUCHI MASATOSHI (JP)
TAKEDA SHUZO (JP)
ADACHI KUNITOMO (JP)
TASHIRO KAORU (JP)
SAKASHITA HIROSHI (JP)
KIUCHI MASATOSHI (JP)
TAKEDA SHUZO (JP)
ADACHI KUNITOMO (JP)
Application Number:
PCT/JP2013/061922
Publication Date:
October 31, 2013
Filing Date:
April 23, 2013
Export Citation:
Assignee:
MITSUBISHI TANABE PHARMA CORP (JP)
International Classes:
C07C225/18; A61K31/137; A61K31/352; A61K31/382; A61K31/665; A61K31/67; A61P3/10; A61P11/02; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P37/02; A61P37/06; A61P37/08; C07D311/86; C07D335/16; C07D409/12; C07F9/655; C07F9/6553
Domestic Patent References:
| WO2007126042A1 | 2007-11-08 | |||
| WO2004074297A1 | 2004-09-02 | |||
| WO1994008943A1 | 1994-04-28 | |||
| WO1996006068A1 | 1996-02-29 | |||
| WO1998045249A1 | 1998-10-15 | |||
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| WO2003029184A1 | 2003-04-10 | |||
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| WO2007069712A1 | 2007-06-21 |
Foreign References:
| JP2004307442A | 2004-11-04 | |||
| JP2009526053A | 2009-07-16 |
Other References:
JASTRZEBSKA-WIESEK,M. ET AL.: "The anticonvulsant, local anesthetic and hemodynamic properties of some chiral aminobutanol derivatives of xanthone", ACTA POLONIAE PHARMACEUTICA, vol. 65, no. 5, 2008, pages 591 - 601, XP055173820
SCIENCE, 2002, pages 346 - 349
NATURE, 2004, pages 355 - 360
TETRAHEDRON, vol. 57, 2001, pages 6531 - 6538
TETRAHEDRON LETTERS, vol. 39, 1998, pages 2933 - 2936
ANGEWANDTE CHEMIE, vol. 42, 2003, pages 5400 - 5449
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 21, 1999, pages 4369 - 4378
JOURNAL OF ORGANIC CHEMISTRY, vol. 71, 2006, pages 3551 - 3558
JOURNAL OF ORGANIC CHEMISTRY, vol. 69, 2004, pages 7765 - 7768
JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, 2000, pages 2946 - 2961
SYNTHESIS, 2006, pages 753 - 755
SCIENCE, 2002, pages 346 - 349
NATURE, 2004, pages 355 - 360
TETRAHEDRON, vol. 57, 2001, pages 6531 - 6538
TETRAHEDRON LETTERS, vol. 39, 1998, pages 2933 - 2936
ANGEWANDTE CHEMIE, vol. 42, 2003, pages 5400 - 5449
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 21, 1999, pages 4369 - 4378
JOURNAL OF ORGANIC CHEMISTRY, vol. 71, 2006, pages 3551 - 3558
JOURNAL OF ORGANIC CHEMISTRY, vol. 69, 2004, pages 7765 - 7768
JOURNAL OF MEDICINAL CHEMISTRY, vol. 43, 2000, pages 2946 - 2961
SYNTHESIS, 2006, pages 753 - 755
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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