Title:
AMINO ACID AND PEPTIDE CONJUGATES AND CONJUGATION PROCESS
Document Type and Number:
WIPO Patent Application WO/2017/145097
Kind Code:
A3
Abstract:
The invention relates to amino acid and peptide conjugates, methods for making amino acid and peptide conjugates, conjugates produced by the methods, and pharmaceutical compositions comprising the conjugates. Methods of eliciting immune responses in a subject and methods of vaccinating a subject, uses of the conjugates for the same, and uses of the conjugates in the manufacture of medicaments for the same are also contemplated.
Inventors:
BRIMBLE MARGARET ANNE (NZ)
WILLIAMS GEOFFREY MARTYN (NZ)
DUNBAR PETER RODERICK (NZ)
VERDON DANIEL (NZ)
WILLIAMS GEOFFREY MARTYN (NZ)
DUNBAR PETER RODERICK (NZ)
VERDON DANIEL (NZ)
Application Number:
PCT/IB2017/051054
Publication Date:
October 05, 2017
Filing Date:
February 24, 2017
Export Citation:
Assignee:
AUCKLAND UNISERVICES LTD (NZ)
International Classes:
C07C229/02; C07C227/16; C07C321/12; C07K1/02; C07K14/00; C07K14/435
Domestic Patent References:
| WO2010028246A2 | 2010-03-11 | |||
| WO2014207708A2 | 2014-12-31 |
Other References:
LU X. J. ET AL.: "Isopentenyl-Diphosphate Isomerase: Irreversible Inhibition by 3-Methyl- 3,4-epoxybutyl Diphosphate", BIOCHEMISTRY, vol. 31, 1992, pages 9955 - 9960, XP055426733
DATABASE REGISTRY 23 April 2015 (2015-04-23), ANONYMOUS, XP055576406, retrieved from STN Database accession no. 1690273-81-4
DATABASE REGISTRY 23 April 2015 (2015-04-23), ANONYMOUS, XP055576409, retrieved from STN Database accession no. 1690246-56-0
DATABASE REGISTRY 22 December 2013 (2013-12-22), ANONYMOUS, XP055576412, retrieved from STN Database accession no. 1500650-08-7
DATABASE REGISTRY 22 December 2013 (2013-12-22), ANONYMOUS, XP055576416, retrieved from STN Database accession no. 1500646-17-2
DATABASE REGISTRY 20 December 2013 (2013-12-20), ANONYMOUS, XP055576418, retrieved from STN Database accession no. 1499966-80-1
DATABASE REGISTRY 18 December 2013 (2013-12-18), ANONYMOUS, XP055576421, retrieved from STN Database accession no. 1498306-02-7
DATABASE REGISTRY 29 October 2009 (2009-10-29), ANONYMOUS, XP055576426, retrieved from STN Database accession no. 1190622-73-1
YANG, S.-H. ET AL.: "Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-Ene Reaction (CLipPA", EUR. J. ORG. CHEM., vol. 2016, no. 15, March 2016 (2016-03-01), pages 2608 - 2616, XP055426738
DATABASE REGISTRY 23 April 2015 (2015-04-23), ANONYMOUS, XP055576406, retrieved from STN Database accession no. 1690273-81-4
DATABASE REGISTRY 23 April 2015 (2015-04-23), ANONYMOUS, XP055576409, retrieved from STN Database accession no. 1690246-56-0
DATABASE REGISTRY 22 December 2013 (2013-12-22), ANONYMOUS, XP055576412, retrieved from STN Database accession no. 1500650-08-7
DATABASE REGISTRY 22 December 2013 (2013-12-22), ANONYMOUS, XP055576416, retrieved from STN Database accession no. 1500646-17-2
DATABASE REGISTRY 20 December 2013 (2013-12-20), ANONYMOUS, XP055576418, retrieved from STN Database accession no. 1499966-80-1
DATABASE REGISTRY 18 December 2013 (2013-12-18), ANONYMOUS, XP055576421, retrieved from STN Database accession no. 1498306-02-7
DATABASE REGISTRY 29 October 2009 (2009-10-29), ANONYMOUS, XP055576426, retrieved from STN Database accession no. 1190622-73-1
YANG, S.-H. ET AL.: "Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-Ene Reaction (CLipPA", EUR. J. ORG. CHEM., vol. 2016, no. 15, March 2016 (2016-03-01), pages 2608 - 2616, XP055426738
Attorney, Agent or Firm:
AJ PARK (NZ)
Download PDF: