Title:
AMINO-CONTAINING COMPOUNDS WHICH INHIBIT MEMAPSIN 2 BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO2006034296
Kind Code:
A3
Abstract:
The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease.
Inventors:
GHOSH ARUN (US)
LEI HUI (US)
DEVASAMUDRAM THIPPESWAMY (US)
LUI CHUNFENG (US)
TANG JORDAN (US)
BILCER GEOFFREY (US)
LEI HUI (US)
DEVASAMUDRAM THIPPESWAMY (US)
LUI CHUNFENG (US)
TANG JORDAN (US)
BILCER GEOFFREY (US)
Application Number:
PCT/US2005/033709
Publication Date:
September 14, 2006
Filing Date:
September 19, 2005
Export Citation:
Assignee:
ZAPAQ INC (US)
UNIV ILLINOIS (US)
OKLAHOMA MED RES FOUND (US)
GHOSH ARUN (US)
LEI HUI (US)
DEVASAMUDRAM THIPPESWAMY (US)
LUI CHUNFENG (US)
TANG JORDAN (US)
BILCER GEOFFREY (US)
UNIV ILLINOIS (US)
OKLAHOMA MED RES FOUND (US)
GHOSH ARUN (US)
LEI HUI (US)
DEVASAMUDRAM THIPPESWAMY (US)
LUI CHUNFENG (US)
TANG JORDAN (US)
BILCER GEOFFREY (US)
International Classes:
C07D277/24; A61K31/415; A61P25/28; C07D231/12; C07D263/32; C07D277/30; C07D413/12; C07D417/12
Foreign References:
| US20040121947A1 | 2004-06-24 |
Other References:
WERMUTH ET AL: "Molecular Variations Based on Isosteric Replacements", PRACTICE OF MEDICINAL CHEMISTRY, 1996, pages 203 - 237, XP002190259
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