AMMONIUM CARBOXYLATE COMPOUND, CRYSTAL FORM AND AMORPHOUS SUBSTANCE THEREOF, AND PREPARATION METHOD THEREFOR

WIPO Patent Application WO/2018/196860

A1

The present invention relates to the field of chemical synthesis, and in particular to an ammonium carboxylate compound, a crystal form and an amorphous substance thereof, and a preparation method therefor. The present invention prepares a compound and a crystal form I, a single crystal, an amorphous substance and a crystal form II thereof. The compound, the crystal forms, the single crystal and the amorphous substance can stably exist, present good solid form, are suitable for patent medicine, and are high in product purity and less individual impurity. The preparation method of the present invention is simple in process, mild in reaction conditions, and high in product yield, and is easy to implement. The product does not require several purification, is high in purity and safety and environmental protection, and is suitable for industrial production.

JP3088137	INDUSTRIAL APPLICABILITY [Title of Invention] 1,4-Dihydronaphthoquinone derivative and method for producing the same.
JP2000344721	PRODUCTION OF SECONDARY AMPHOACETATE AND AMPHODIACETATE
WO/2001/094294	FUNGICIDES

ZHANG BO (CN)
DING XIAOHUA (CN)
DAI DONGCHENG (CN)
LEI SIJUN (CN)
LIU XUEMING (CN)
DUAN PANPAN (CN)
CHEN YONGKAI (CN)
WANG CHAODONG (CN)

PCT/CN2018/084913

November 01, 2018

April 27, 2018

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WUHAN LL SCIENCE AND TECH DEVELOPMENT CO LTD (CN)
WUHAN QR PHARMACEUTICALS CO LTD (CN)

C07C233/47; A61K31/216; A61K31/41; A61P9/04; A61P9/12; C07C211/05; C07C215/08; C07D295/027

WO2011088797A1

2011-07-28

CN105693543A	2016-06-22
CN106397273A	2017-02-15
CN106138043A	2016-11-23
CN201710300300A	2017-04-28
CN103709154A	2014-04-09

See also references of EP 3611160A4

WUHAN ORIGINTELLIGENCE IP LAW FIRM (CN)

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