AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF

Title:

AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2012/016097

Kind Code:

A3

Abstract:

The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses.

Inventors:

CHANG FRANK (US)
SCOTT ROBERT (US)
HUANG JINYU (US)
MEDINA ARTURO N (US)
SMITH DAWN A (US)
SANDERS LAURA ANN (US)
PRUITT JOHN DALLAS (US)

Application Number:

PCT/US2011/045809

Publication Date:

August 15, 2013

Filing Date:

July 29, 2011

Export Citation:

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Assignee:

NOVARTIS AG (CH)
CHANG FRANK (US)
SCOTT ROBERT (US)
HUANG JINYU (US)
MEDINA ARTURO N (US)
SMITH DAWN A (US)
SANDERS LAURA ANN (US)
PRUITT JOHN DALLAS (US)

International Classes:

C08F26/02; C08F226/00

Foreign References:

US20080231798A1	2008-09-25
US20100120938A1	2010-05-13
US20080234457A1	2008-09-25
US20090143499A1	2009-06-04
US20100296049A1	2010-11-25

Other References: