Title:
AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/093751
Kind Code:
A3
Abstract:
The invention provides an amphiphilic siloxane-containing vinylic monomer of formula (I), polymers made therefrom, an actinically- crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane- containing vinylic monomer of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing vinylic monomer of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention. Formula (I): Q-Xl-hl_-X2-BSi, in which: Q contains a terminal vinylic group, BSi is a siloxane containing hydrophobic group, while the variable hl_ represents a hydrophilic group containing oligomers of -[N(C(=0)R)-CH2-CH2]-, polypeptide segments or polymeric segment from hydrophilic vinylic monomers. The variables are more closely defined in the claims.
Inventors:
CHANG FRANK (US)
Application Number:
PCT/US2013/074890
Publication Date:
August 28, 2014
Filing Date:
December 13, 2013
Export Citation:
Assignee:
NOVARTIS AG (CH)
CHANG FRANK (US)
CHANG FRANK (US)
International Classes:
C07F7/08; C08G81/00; G02B1/04
Domestic Patent References:
| WO2013098966A1 | 2013-07-04 | |||
| WO2000037541A1 | 2000-06-29 | |||
| WO2010102747A2 | 2010-09-16 |
Foreign References:
| JP2012017285A | 2012-01-26 |
Other References:
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KOMAROV, N. V. ET AL: "Synthesis of vinyl ethers of .gamma.-silicon-containing aminoethanols", XP002721812, retrieved from STN Database accession no. 1968:21985
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KUMAR, KANTA ET AL: "Hydrosilation of alkenyl azlactones", XP002721813, retrieved from STN Database accession no. 1993:626042
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KOMAROV, N. V. ET AL: "Preparation of vinyl ethers of organosilicon aminoethanols", XP002721814, retrieved from STN Database accession no. 1968:39803
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KUMAR, KANTA ET AL: "Hydrosilation of alkenyl azlactones", XP002721813, retrieved from STN Database accession no. 1993:626042
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KOMAROV, N. V. ET AL: "Preparation of vinyl ethers of organosilicon aminoethanols", XP002721814, retrieved from STN Database accession no. 1968:39803
Attorney, Agent or Firm:
ZHOU, Jian S. (Patent Department11460 Johns Creek Parkwa, Johns Creek Georgia, US)
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