ANALYSIS OF GENE EXPRESSION PROFILES USING SEQUENTIAL HYBRIDIZATION

Title:

ANALYSIS OF GENE EXPRESSION PROFILES USING SEQUENTIAL HYBRIDIZATION

Document Type and Number:

WIPO Patent Application WO2003016574

Kind Code:

A9

Abstract:

This invention relates generally to analysis of gene expression profiles. In particular, the present invention provides a method for a method for analyzing gene expression profiles of a cell, which method comprises: (a) providing for isolated mRNA or cDNA target sequences from a cell; (b) sequentially hybridizing said isolated mRNA or cDNA target sequences with a plurality of neucleotide probes; and (c) assessing the sequential hybridization between said isolated mRNA or cDNA target sequences and said plurality of nucleotide probes to analyze gene expression profiles of said cell. Systems for analyzing gene expression profiles are also provide. Optical devices for detecting hybridization signal are further provided.

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Inventors:

SHAO ZHIFENG (US)
SHENG SITONG (US)
LIANG SHOUDAN (US)

Application Number:

PCT/US2002/026073

Publication Date:

December 23, 2004

Filing Date:

August 16, 2002

Export Citation:

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Assignee:

SHAO ZHIFENG (US)
SHENG SITONG (US)
LIANG SHOUDAN (US)

International Classes:

C12Q1/68; C12Q1/6809; C12Q1/6876; (IPC1-7): C12Q1/68

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