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Title:
ANALYTIC METHOD FOR DIAGNOSING OVARIAN CANCER RESISTANT TO PACLITAXEL
Document Type and Number:
WIPO Patent Application WO/2024/063562
Kind Code:
A1
Abstract:
The present invention provides an analytic method comprising a step for measuring the expression level of a gene encoding at least one deubiquitinating enzyme, selected from the group consisting of USP3, USP9X, USP26, USP34, COPS5, OTUD6A, and OTUD7A, in a tumor cell sample isolated in vitro from a patient with ovarian cancer resistant to paclitaxel, which is an anticancer drug widely used in the treatment of ovarian cancer, the expression level of the gene being measured in order to provide information needed to diagnose the patient with ovarian cancer. Also, the present invention provides a kit for diagnosing ovarian cancer resistant to paclitaxel, the kit comprising a molecule capable of measuring the expression level of a gene encoding the protein.

Inventors:
BAEK KWANG-HYUN (KR)
KO HEE-GYEONG (KR)
KIM YE-WON (KR)
Application Number:
PCT/KR2023/014392
Publication Date:
March 28, 2024
Filing Date:
September 21, 2023
Export Citation:
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Assignee:
UNIV CHA IND ACAD COOP FOUND (KR)
International Classes:
C12Q1/6886; C12Q1/6851
Domestic Patent References:
WO2012092426A12012-07-05
Foreign References:
KR102082462B12020-02-27
KR20180022968A2018-03-06
KR101953300B12019-02-28
KR20200115450A2020-10-07
Attorney, Agent or Firm:
OH, Kook-Jin (KR)
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