Title:
ANDROGEN RECEPTOR ACTIVITY REGULATOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/151662
Kind Code:
A1
Abstract:
Provided are an androgen receptor activity regulator and the use thereof. The androgen receptor activity regulator has a structure as represented by formula 1-I or formula 2-I, wherein R1-R7, X, ring A, ring B, ring C, n, m, p, Z1 and Z2 are as described herein. Further provided are a pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, isotopic substitute, polymorph, prodrug or metabolite of a compound of formula 1-I or formula 2-I, and a pharmaceutical composition thereof and the pharmaceutical use thereof.
Inventors:
ZHENG QIANGANG (CN)
JIANG XIANGQING (CN)
LI JING (CN)
ZENG QINGLONG (CN)
XU MING (CN)
CHEN YAOZHONG (CN)
ZHONG XIAOFENG (CN)
LI GUO (CN)
ZHU JIDONG (CN)
JIANG XIANGQING (CN)
LI JING (CN)
ZENG QINGLONG (CN)
XU MING (CN)
CHEN YAOZHONG (CN)
ZHONG XIAOFENG (CN)
LI GUO (CN)
ZHU JIDONG (CN)
Application Number:
PCT/CN2023/075450
Publication Date:
August 17, 2023
Filing Date:
February 10, 2023
Export Citation:
Assignee:
ETERN BIOPHARMA SHANGHAI CO LTD (CN)
International Classes:
C07D239/42; A61K31/381; A61K31/382; A61K31/506; A61P35/00; C07D333/48; C07D335/02; C07D403/02; C07D403/12; C07D403/14; C07D487/04
Domestic Patent References:
| WO2020198710A1 | 2020-10-01 | |||
| WO2021138392A1 | 2021-07-08 |
Foreign References:
| CN105732614A | 2016-07-06 |
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
Download PDF: