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Title:
ANGIO-OCT-BASED DYNAMIC FUNCTIONAL RETINAL BLOOD FLOW IMAGING APPARATUS AND IMAGING METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/000846
Kind Code:
A1
Abstract:
Provided is an angio-OCT-based dynamic functional retinal blood flow imaging apparatus, comprising an angio-OCT sample optical path and an angio-OCT signal acquisition path, and further comprising a visual stimulation module arranged on the same axis as a sample arm optical path, the visual stimulation module projecting a stimulation image to different parts of the retina in the eye by means of a heat mirror DM. Further provided is an imaging method for an angio-OCT visual stimulation-induced retinal dynamic functional blood flow change image of an angio-OCT-based dynamic functional retinal blood flow imaging apparatus. The apparatus and the method focus on the functional characteristics of a visual system, and based on the special functional unit, "vascular nerve coupling", of a central nervous system, dynamic functional retinal blood flow imaging combined with visual stimulation is developed on the basis of existing angio-OCT imaging technology, thereby further improving the ability of existing angio-OCT in the aspects of early diagnosis and disease progression judgment of retinal vascular diseases, and developing the detection capability of angio-OCT on early diagnosis and disease progression of retinal neurological diseases such as glaucoma.

Inventors:
ZHANG SHAODAN (CN)
SHEN MEIXIAO (CN)
LIN SIGENG (CN)
YOU RUIRONG (CN)
Application Number:
PCT/CN2022/120223
Publication Date:
January 04, 2024
Filing Date:
September 21, 2022
Export Citation:
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Assignee:
THE EYE HOSPITAL OF WENZHOU MEDICAL UNIV (CN)
International Classes:
A61B3/10; A61B5/00
Domestic Patent References:
WO2021203029A12021-10-07
Foreign References:
US20200375452A12020-12-03
CN110313889A2019-10-11
CN111543971A2020-08-18
CN112638233A2021-04-09
JP2019205816A2019-12-05
US20220183553A12022-06-16
RU2705403C12019-11-07
Other References:
ZHONG, LITING; XIANG, WU; ZHONG, YANFENG; YI, KE; ZHANG, SHAOCHONG: "Application Progress of Angio_OCT in the Comprehensive Diagnosis and Treatment Process of Fundus Diseases", JOURNAL OF MOLECULAR DIAGNOSTICS AND THERAPY, CHINA, vol. 12, no. 11, 30 November 2020 (2020-11-30), China, pages 1429 - 1433, XP009552124, ISSN: 1674-6929
Attorney, Agent or Firm:
WENZHOU JINOU PATENT LAW OFFICE (GENERAL PARTNERSHIP) (CN)
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