Title:
ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR COMPOSITE, AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/125031
Kind Code:
A1
Abstract:
Provided are a supramolecular composite comprising an angiotensin II receptor (AT1) blocking compound, a neutral endopeptidase inhibitor (NEPi), and a pharmaceutically acceptable cation. The invention further provides a method for preparing the composite and an application of the composite for preparing a pharmaceutical product for treating heart failure.
Inventors:
YAN JIE (CN)
XU WENJIE (CN)
LI SONG (CN)
ZHENG YANXIN (CN)
ZHI JIANQIONG (CN)
XU WENJIE (CN)
LI SONG (CN)
ZHENG YANXIN (CN)
ZHI JIANQIONG (CN)
Application Number:
PCT/CN2017/071625
Publication Date:
July 27, 2017
Filing Date:
January 19, 2017
Export Citation:
Assignee:
SHENZHEN SALUBRIS PHARM CO LTD (CN)
International Classes:
C07D403/10; A61K31/216; A61K31/41; A61P9/00; C07C231/12; C07C233/47
Domestic Patent References:
| WO2007056546A1 | 2007-05-18 |
Foreign References:
| CN106146472A | 2016-11-23 | |||
| CN106138041A | 2016-11-23 | |||
| CN105669581A | 2016-06-15 | |||
| CN105503760A | 2016-04-20 | |||
| CN104826115A | 2015-08-12 |
Other References:
See also references of EP 3406610A4
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