ANHYDROUS ANTIPERSPIRANT AEROSOL COMPOSITION WHICH PROVIDES

A SOFT FOCUS EFFECT FIELD OF THE INVENTION

The present invention relates to an anhydrous antiperspirant aerosol cosmetic composition comprising one or more aluminum-containing antiperspirant ingredient; about 1 % to about 5% by weight of one or more silicone elastomer; one or more modified clay suspending agent; and an oil system for improving the soft focus effect of underarm skin.

BACKGROUND OF THE INVENTION

Sweating, though a natural bodily function, results in the formation of wet patches on human skin and/or clothing. Moreover, the sweat secreted from sweat glands has a tendency to form a malodorous odor due to its interaction with the many microorganisms which reside on the skin surface, particularly the skin of the underarm. These two phenomena are deemed to be undesirable in many societies.

Products are commonly available which help to address both phenomena. More particularly, antiperspirant products possess ingredients which inhibit/suppress sweating, whereas deodorant products possess ingredients that mask the malodors caused by sweat.

A large number of women remove their armpit hair by shaving, waxing, tweezing, or depilatories. Hair removal methods can result in skin redness and blotchiness. Furthermore, as a person ages, underarm skin loses its elasticity and becomes rougher and more wrinkled. Moreover, the ingredients used to inhibit/suppress sweating may also result in skin irritation.

While antiperspirant and/or deodorant compositions are used to reduce underarm wetness and/or odor, some consumers seek additional benefits. Therefore, there is a consumer need to improve the visual appearance of the underarm skin while at the same time addressing underarm wetness and/or odor.

Anhydrous antiperspirant aerosol compositions which reduce visual imperfections of underarm skin and/or improve tone, smoothness, and/or radiance thereby producing a soft focus effect to the underarm skin are disclosed, for example, in WO 2010/057968. The disclosed compositions contain particulate aluminum antiperspirant salt, oil, a smoothing aid which comprises up to 2.5% wax and/or mica, and a propellant. The applicants have recognized that severe aesthetic and performance problems still exist in most anhydrous antiperspirant aerosol products. Accordingly, applicants have now identified a novel anhydrous antiperspirant aerosol cosmetic composition which blurs the appearance of imperfections such as lines and dark spots on the underarm skin, and is sensorially pleasant to apply.

SU MMARY O F TH E INVENTION

The present invention relates to an anhydrous antiperspirant aerosol cosmetic composition comprising:

(a) one or more aluminum-containing antiperspirant ingredient;

(b) 1 % to 5% by weight of one or more silicone elastomer;

(c) one or more modified clay suspending agent;

(d) an oil system comprising:

i. one or more volatile hydrocarbon; and

ii. one or more fatty acid ester; and

(e) one or more propellant.

The present invention is also directed to a process for suppressing sweat and odor from forming on human skin involving applying the above-disclosed composition onto a surface of the human skin. The present invention is also directed to a process for bluring the appearance of imperfections such as lines and dark spots on the underarm skin thereby providing a soft focus effect.

The compositions according to the invention may be placed in a dispensing means and applied by spraying, for example an aerosol spray.

Applicants have unexpectedly discovered that the above-described composition not only controls perspiration and body odor, but also blurs the appearance of imperfections such as lines and dark spots thereby providing a soft focus effect to the underarm skin.

DETAILED DESCRIPTION OF THE INVENTION

The compositions of the present invention control perspiration and optionally, also body odor from localized areas of the body such as the underarm. The compositions of the present invention blur the appearance of imperfections such as lines and dark spots on the underarm skin thereby providing a soft focus effect.

"One or more" as used herein means at least one and thus includes individual components as well as mixtures/combinations.

"Anhydrous," as used herein, means that the composition contains no appreciable amount of water, for example, no more than 2% by weight, or no more than 1 % by weight, or no more than 0.5% by weight, based on the weight of the composition.

"Substituted," as used herein, means comprising one or more substituents. Non-limiting examples of substituents include atoms, such as oxygen atoms and nitrogen atoms, as well as functional groups, such as hydroxyl groups, ether groups, alkoxy groups, acyloxyalkyl groups, oxyalkylene groups, polyoxyalkylene groups, carboxylic acid groups, amine groups, acylamino groups, amide groups, halogen containing groups, ester groups, thiol groups, sulphonate groups, thiosulphate groups, siloxane groups, and polysiloxane groups. The substituent(s) may be further substituted.

"Polymers," as defined herein, include homopolymers and copolymers formed from at least two different types of monomers.

"INCI" is an abbreviation of International Nomenclature of Cosmetic Ingredients, which is a system of names provided by the International Nomenclature Committee of the Personal Care Products Council to describe personal care ingredients.

"Cosmetically acceptable" means that the item in question is compatible with any keratinous substrate. For example, "cosmetically acceptable carrier" means a carrier that is compatible with any keratinous substrate.

The compositions and methods of the present invention can comprise, consist of, or consist essentially of the essential elements and limitations of the invention described herein, as well as any additional or optional ingredients, components, or limitations described herein or otherwise useful.

Other than in the operating examples, or where otherwise indicated, all numbers expressing quantities of ingredients and/or reaction conditions are to be understood as being modified in all instances by the term "about."

All percentages, parts and ratios herein are based upon the total weight of the compositions of the present invention, unless otherwise indicated.

As used herein, all ranges provided are meant to include every specific range within, and combination of subranges between, the given ranges. Thus, a range from 1 -5, includes specifically 1 , 2, 3, 4 and 5, as well as subranges such as 2- 5, 3-5, 2-3, 2-4, 1 -4, etc.

As used herein a range of ratios is meant to include every specific ratio within, and combination of subranges between, the given ranges.

In an embodiment, the present invention is directed to an anhydrous antiperspirant aerosol cosmetic composition comprising:

An anhydrous antiperspirant aerosol cosmetic composition comprising:

(a) from 4% to 10% by weight of one or more aluminum-containing antiperspirant ingredients;

(b) from 1 % to 5% by weight of one or more silicone elastomers;

(c) from 0.2% to 2% by weight of one or more modified clay suspending agents;

(d) from 1 % to 15% by weight of an oil system comprising:

i. one or more volatile hydrocarbon; and

ii. one or more fatty acid ester; and

(e) one or more propellants

In a further embodiment, the present invention is directed to method of improving the appearance of imperfections such as lines and dark spots on underarm skin comprising topically applying to the underarm skin an anhydrous antiperspirant aerosol cosmetic composition comprising:

(a) from 4% to 10% by weight of one or more aluminum-containing antiperspirant ingredients;

(b) from 1 % to 5% by weight of one or more silicone elastomers;

(c) from 0.2% to 2% by weight of one or more modified clay suspending agents;

(d) from 1 % to 15% by weight of an oil system comprising:

i. one or more volatile hydrocarbon; and

ii. one or more fatty acid ester; and

(e) one or more propellants

The compositions according to the invention have a dry feel and soft touch on the skin while controlling perspiration and body odor.

The present invention also is directed to a process for controlling perspiration and body odor comprising applying the composition according to the invention to localized areas of the body such as the underarm.

Other subjects and characteristics, aspects and advantages of the invention will emerge even more clearly on reading the description and the example that follows. ANTIPERSPIRANT INGREDIENT

The term "antiperspirant ingredient" means any substance capable of reducing the flow of sweat. The antiperspirant ingredients which can be used according to the invention are preferably chosen from aluminium and/or zirconium salts, complexes of zirconium chlorohydrate and of aluminium chlorohydrate with an amino acid, and the mixtures thereof.

Non-limiting examples of aluminum salts useful in the invention include, for example, aluminium chlorohydrate in the activated or nonactivated form, aluminium chlorohydrex, the aluminium chlorohydrex polyethylene glycol complex, the aluminium chlorohydrex propylene glycol complex, aluminium dichlorohydrate, the aluminium dichlorohydrex polyethylene glycol complex, the aluminium dichlorohydrex propylene glycol complex, aluminium sesquichlorohydrate, the aluminium sesquichlorohydrex polyethylene glycol complex, the aluminium sesquichlorohydrex propylene glycol complex, aluminium sulphate buffered by sodium aluminium lactate, and the mixtures thereof.

Non-limiting examples of complexes of zirconium chlorohydrate and aluminium chlorohydrate with an amino include, for example, aluminium zirconium octachlorohydrate, aluminium zirconium pentachlorohydrate, aluminium zirconium tetrachlorohydrate, aluminium zirconium trichlorohydrate, and the mixtures thereof.

Complexes of zirconium chlorohydrate and of aluminium chlorohydrate with an amino acid are generally known under the name ZAG (when the amino acid is glycine). They are disclosed, for example, in patent US-3 792 068. The ZAG complexes usually exhibit an Al/Zr quotient ranging from about 1 .67 to 12.5 and a Metal/CI quotient ranging from about 0.73 to 1 .93. Non-limiting examples of these complexes include, for example, aluminium zirconium octachlorohydrex glycine, aluminium zirconium pentachlorohydrex glycine, aluminium zirconium tetrachloro- hydrex glycine aluminium zirconium trichlorohydrex glycine complexes, and mixtures thereof.

Preferably, the antiperspirant ingredient is aluminium chlorohydrate, in particular the product sold by SummitReheis under the name CHLORHYDROL ^® 50, aluminum sesquichlorohydrate, in particular the product sold by SummitReheis under the name REACH 301 , aluminum zirconium tetrachlorohydrex GLY (INCI name), in particular the product sold by SummitReheis under the name REACH AZP-908, and mixtures thereof. The antiperspirant ingredient is preferably present in the composition according to the invention in an amount of from about 4% to about 10% by weight, preferably from about 5% to about 8% by weight, and most preferably from about 5% to about 7% by weight, based on the total weight of the composition.

SILICONE ELASTOMER

The term "silicone elastomer" means a supple, deformable organopolysiloxane with viscoelastic properties and especially with the consistency of a sponge or a supple sphere. Its modulus of elasticity is such that this material withstands deformation, has a limited ability to extend and to contract, and is capable of regaining its original shape after stretching.

The silicone elastomer is more particularly a crosslinked organopolysiloxane elastomer. The organopolysiloxane elastomer may be obtained by crosslinking addition reaction of diorganopolysiloxane containing at least one hydrogen bonded to silicon and of diorganopolysiloxane containing ethylenically unsaturated groups bonded to silicon, especially in the presence of a platinum catalyst; or by dehydrogenation crosslinking condensation reaction between a diorganopolysiloxane containing hydroxyl end groups and a diorganopolysiloxane containing at least one hydrogen bonded to silicon, especially in the presence of an organotin; or by crosslinking condensation reaction of a diorganopolysiloxane containing hydroxyl end groups and of a hydrolysable organopolysilane; or by thermal crosslinking of organopolysiloxane, especially in the presence of an organoperoxide catalyst; or by crosslinking of organopolysiloxane via high-energy radiation such as gamma rays, ultraviolet rays or an electron beam.

The silicone elastomer is advantageously a non-emulsifying elastomer. The term "non-emulsifying" defines organopolysiloxane elastomers not containing any hydrophilic chains, and in particular not containing any polyoxyalkylene units (especially polyoxyethylene or polyoxypropylene) or any polyglyceryl units. Thus, according to one particular mode of the invention, the composition comprises an organopolysiloxane elastomer free of polyoxyalkylene units and of polyglyceryl units.

Non-emulsifying elastomers are described especially in patents EP 242

219, EP 285 886 and EP 765 656 and in patent application JP-A-61 -194009.

The silicone elastomer is generally in the form of a gel, a paste or a powder, but advantageously in the form of a gel in which the silicone elastomer is dispersed in a linear silicone oil (dimethicone) or cyclic silicone oil (e.g.: cyclopentasiloxane), advantageously in a linear silicone oil.

According to a particular mode, use is made of a gel of silicone elastomer dispersed in a silicone oil chosen from a non-exhaustive list comprising cyclopentadimethylsiloxane, dimethicones, dimethylsiloxanes, methyl trimethicone, phenyl methicone, phenyl dimethicone, phenyl trimethicone and cyclomethicone, preferably a linear silicone oil chosen from polydimethylsiloxanes (PDMS) or dimethicones with a viscosity at 25°C ranging from 1 to 500 cSt, optionally modified with optionally fluorinated aliphatic groups, or with functional groups such as hydroxyl, thiol and/or amine groups.

According to a preferred embodiment, the composition according to the invention comprises at least one crosslinked silicone elastomer having the INCI name "dimethicone crosspolymer" or "dimethicone (and) dimethicone crosspolymer", with preferably a dimethicone having a viscosity ranging from 1 to 100 cSt, in particular from 1 to 10 cSt at 25°C, such as the mixture of polydimethylsiloxane crosslinked with hexadiene/polydimethylsiloxane (16% by weight) in dimethicone (5 cSt) sold under the name DC 9041 Dow Corning or the mixture of polydimethylsiloxane crosslinked with hexadiene/polydimethylsiloxane (16% by weight) in dimethicone (2 cSt) sold under the name Dow Corning EL-9240 ^® silicone elastomer blend Dow Corning.

The silicone elastomer is preferably present in the composition according to the invention in an amount of from about 1 % to about 5% by weight, preferably from about 1 % to about 2% by weight, and most preferably from about 1 .4 % to about 1 .8% by weight, based on the total weight of the composition.

SUSPENDING AGENT

The composition of the present invention contains a modified clay suspending agent which is preferably chosen from cationically-modified smectite clays. Smectite clays may be represented by the chemical formula (Mg,Li) ₃ SiO ₄ (OH,F) ₂ and include hectorite, bentonite, montmorillonite, attapulgite, and sepiolite. The clays are modified with a chemical compound preferably chosen from quaternary amines. Examples include the reaction product of hectorite and distearyldimonium chloride known by the INCI name disteardimonium hectorite sold under the tradename BENTONE ^® 38 VCG or BENTONE ^® Gel by the company Elementis Specialties, or the reaction product of bentonite and quaternary ammonium stearalkonium chloride known by the INCI name stearalkonium bentonite sold under the tradename Tixogel ^® MP 250 by the company BYK Additives & Instruments or the reaction product of quaternium-18 and bentonite known by the INCI name quaternium-18 bentonite sold under the tradename Bentone ^® 34 by the company Elementis Specialties.

Preferred modified clay suspending agents according to the present invention include hectorite and bentonite modified with quaternary amines. A preferred suspending agent according to the present invention includes disteardimonium hectorite.

The suspending agent is preferably present in the composition according to the invention in an amount of from about 0.2% to about 2% by weight, preferably from about 0.3% to about 1 % by weight, and most preferably from about 0.3% to about 0.6% by weight, based on the total weight of the composition.

OIL SYSTEM

The composition of the present invention contains an oil system comprised of one or more volatile hydrocarbon and one or more fatty acid ester.

The oil system is preferably present in the composition according to the invention in an amount of from about 1 % to about 15% by weight, based on the total weight of the composition.

VOLATILE HYDROCARBON

The oil system of the present invention contains one or more volatile hydrocarbon. The term "hydrocarbon" is intended to mean an oil comprising carbon and hydrogen atoms. For the purposes of the invention, the term "volatile hydrocarbon" is intended to mean a hydrocarbon that is capable of evaporating on contact with the skin or the keratin fibers in less than one hour, at ambient temperature and atmospheric pressure. The volatile hydrocarbons of the invention are volatile cosmetic oils which are liquid at ambient temperature and which have a non-zero vapor pressure, at ambient temperature and atmospheric pressure, ranging in particular from 0.13 Pa to 40 000 Pa (10 ^"3 to 300 immHg), in particular ranging from 1 .3 Pa to 13 000 Pa (0.01 to 100 immHg) and more particularly ranging from 1 .3 Pa to 1300 Pa (0.01 to l O mmHg).

Among the volatile hydrocarbons mention may be made of straight- chain hydrocarbons containing from 8 to 16 carbon atoms, for example, dodecane and hexadecane, and branched-chain hydrocarbons containing from 8 to 16 carbon atoms, for example, isododecane, isodecane, isohexadecane, and C ₈ -Ci ₆ isoalkanes of petroleum origin (also known as isoparaffins) known under the INCI names C1 1 -13 isoparaffin and C8-9 isoparaffin sold under the tradename ISOPAR™ by ExxonMobil.

A preferred volatile hydrocarbon according to the present invention includes isododecane.

The volatile hydrocarbon is preferably present in the composition according to the invention in an amount of from about 1 % to about 10% by weight, preferably from about 2% to about 5% by weight, and most preferably from about 2% to about 3% by weight, based on the total weight of the composition.

FATTY ACID ESTER

The oil system of the present invention contains one or more fatty acid ester containing 7 to 31 carbon atoms. Examples of suitable fatty acid esters containing 7 to 31 carbon atoms for use in the present invention include, but are not limited to, dicaprylyl carbonate, 2-ethylhexyl isononanoate, isononyl isononanoate, isopropyl palmitate, myristyl palmitate, C1 2-C1 5 alkyl benzoate, and isodecyl isononate.

Preferred fatty acid esters according to the present invention include isononyl isononanoate, isopropyl palmitate, or mixtures thereof.

The fatty acid ester is preferably present in the composition according to the invention in an amount of from about 0.2% to about 15% by weight, preferably from about 0.4% to about 5% by weight, and most preferably from about 0.4% to about 3% by weight, based on the total weight of the composition.

PLANT-DERIVED OIL (OPTIONAL)

The oil system of the present invention may optionally contain one or more plant-derived oil having a melting point from 1 0°C to 40°C, such as from about 1 2°C to 38°C, preferably from about 1 6°C to 32°C.

Plant-derived oils are those typically extracted from relevant parts of the plant such as the seed, fruit or leaf, although equivalents which can be synthetically manufactured may be employed as well. Suitable plant derived oils include, but are not limited to, cocos nucifera (coconut) oil, babassu (orbignya olifera seed) oil, safflower oil, palm kernel oil, cottonseed oil, pracaxi oil (known by the INCI name pentaclethra macroloba seed oil), andiroba oil (known by the INCI name carapa guaianensis seed oil), pataua oil (known by the INCI name oenocarpus bataua fruit oil), and buriti oil (known by the INCI name mauritia flexuosa fruit oil). A preferred plant-derived oil according to the present invention includes cocos nucifera (coconut) oil.

When present, the plant-derived oil is preferably present in the composition according to the invention in an amount of from about 0.5% to about 5% by weight, preferably from about 1 % to about 5% by weight, and most preferably from about 2% to about 3% by weight, based on the total weight of the composition.

LOWER ALKYL ETHER OF POLYPROPYLENE GLYCOLS (OPTIONAL)

The oil system of the present invention may optionally contain one or more lower alkyl ether of polypropylene glycols ("PPG alkyl ethers"). PPG alkyl ethers are liquid, water-insoluble propoxylated fatty alcohols, having the molecular formula of RO(CH ₂ CHOCH ₃ )n; wherein "R" is a straight-chained or branched C ₄ to C ₂₂ alkyl group; and "n" is in the range between 4 and about 50.

Among the PPG alkyl ethers mention may be made of PPG-12 butyl ether, PPG-14 butyl ether, PPG-15 butyl ether, PPG-16 butyl ether, PPG-17 butyl ether, PPG-18 butyl ether, and PPG-20 butyl ether.

A preferred PPG alkyl ether according to the present invention includes PPG-14 butyl ether.

When present, the PPG alkyl ether is preferably present in the composition according to the invention in an amount from about 0.5% to about 5% by weight, preferably from about 1 % to about 5% by weight, and most preferably from about 2% to about 3% by weight, based on the total weight of the composition.

PROPELLANT

Propellants generally used in products of this type and that are well known to those skilled in the art are, for example, dimethyl ether (DME), volatile hydrocarbons such as n-butane, propane, isobutane and mixtures thereof, carbon dioxide gas, nitrous oxide, nitrogen, or compressed air.

The compositions as defined previously and the propellant(s) may be in the same compartment or in different compartments in the aerosol container. The dispensing means, which forms a part of the aerosol device, is generally composed of a dispensing valve controlled by a dispensing head, itself comprising a nozzle via which the aerosol composition is vaporized. The container comprising the pressurized composition can be opaque or transparent. It can be made of glass, of polymer or of metal, optionally covered with a protective lacquer layer. The weight ratio between the liquid phase and the propellant is from about 5:95 to about 50:50 and more preferably from about 10:90 to about 20:80.

The compositions according to the invention may additionally comprise cosmetic adjuvants chosen from fragrances, pigments, chelating agents, softeners, antioxidants, opacifiers, stabilizers, moisturizing agents, vitamins, bactericides, preservatives, polymers, thickening agents, or any other ingredient commonly used in cosmetics for this type of application.

Of course, a person skilled in the art will take care to choose this or these optional additional compounds so that the advantageous properties intrinsically attached to the composition in accordance with the invention are not, or not substantially, detrimentally affected by the envisaged addition or additions.

The amounts of these various constituents which can be present in the composition according to the invention are those conventionally used in the art.

The following examples serve to illustrate the invention without however exhibiting a limiting character. In these examples the amounts of the composition ingredients are given as weight percentages relative to the total weight of the composition.

EXAMPLES TABLE 1 : INVENTIVE EXAMPLES

Example Example

US INCI Name

1 2

ISOBUTANE (and) BUTANE (and) PROPANE 85 85

ALUMINUM CHLOROHYDRATE 5,25 7

DIMETHICONE CROSSPOLYMER

(Dow Corning EL-9240 Silicone Elastomer Blend,

1 ,65 0

13 wt. % dimethicone crosspolymer in 2 cSt

dimethicone)

DIMETHICONE (and) DIMETHICONE

CROSSPOLYMER

(Dow Corning 9041 Silicone Elastomer Blend, 16 0 1 ,58 wt. % dimethicone crosspolymer in 5 cSt

dimethicone)

DISTEARDIMONIUM HECTORITE 0,53 0,39 Example Example

US INCI Name

1 2

ISODODECANE 3 2,25

ISOPROPYL PALMITATE 0 2,25

ISONONYL ISONONANOATE 0,45 0

COCOS NUCIFERA (COCONUT) OIL 0,75 0

PPG-14 BUTYL ETHER 1 ,8 0

FRAGRANCE 1 ,4 1 ,4

PROPYLENE CARBONATE 0,17 0.13

TOTAL (%) 100 100

TABLE 2: INVENTIVE EXAMPLES

Example Example

US INCI Name

3 4

ISOBUTANE (and) BUTANE (and) PROPANE 83,65 81 ,58

ALUMINUM CHLOROHYDRATE 5,25 7

DIMETHICONE CROSSPOLYMER

(Dow Corning EL-9240 Silicone Elastomer Blend,

3,0 0

13 wt. % dimethicone crosspolymer in 2 cSt

dimethicone)

DIMETHICONE (and) DIMETHICONE

CROSSPOLYMER

(Dow Corning 9041 Silicone Elastomer Blend, 16 0 5,0 wt. % dimethicone crosspolymer in 5 cSt

dimethicone)

DISTEARDIMONIUM HECTORITE 0,53 0,39

ISODODECANE 3 2,25

ISOPROPYL PALMITATE 0 2,25

ISONONYL ISONONANOATE 0,45 0

COCOS NUCIFERA (COCONUT) OIL 0,75 0

PPG-14 BUTYL ETHER 1 ,8 0

FRAGRANCE 1 ,4 1 ,4

PROPYLENE CARBONATE 0,17 0.13 Example Example

US INCI Name

3 4

TOTAL (%) 100 100

In making example 1 ,the following procedure was used. Isononyl isononanoate, PPG-14 butyl ether, and fragrance were combined and added to dimethicone crosspolymer dissolved in isododecane. The mixture was stirred for 10 minutes. Disteardimonium hectorite, propylene carbonate, and aluminum chlorohydrate were added sequentially followed my mixing after each addition until dispersion of the powders was complete. The similar processes were used to prepare inventive Examples 2, 3, and 4.

To prepare an aerosol spray, the resulting mixture of Examples 1 , 2, 3, and 4, respectively was added to a spray can followed by the addition of propellant gas wherein the ratio of the composition to gas was from about 10:90 to about 20:80.

ASSESSMENT OF INVENTIVE EXAMPLE ON RECONSTRUCTED SKIN

Samples were evaluated to assess the extent to which visible skin imperfections were reduced or blurred. Samples were applied to reconstructed skin of the Skin FX ^® type. The reconstructed skin was evaluated using a DermaScore Plus ^® device. DermaScore Plus ^® is an imaging device dedicated to a direct observation and acquisition of various characteristics of the skin surface (color, pigmentation, pores, dryness, optical properties, or relief). Images are captured under a high magnification and under different lighting configurations to highlight the skin relief, based upon parallel polarized images. Images were captured and an analysis carried out by visual comparison with the images from an atlas. The atlas images were graded from 1 (no/slight visible imperfections) through 8 (very noticeable visible imperfections). The results are summarized in Table 2. The results demonstrate a significant reduction in visible imperfections after application of the composition according to Example 1 .

TABLE 2: VISUAL ASSESSMENT ON RECONSTRUCTED SKIN

Before After

Product

Product Application Product Application

Example 1

Aerosol Spray Grade 5 Grade 1

(15:85 liquid:propellant)

Example 2 Grade 5 Grade 2,4 Before After

Product

Product Application Product Application

Aerosol Spray

(15:85 liquid:propellant)

Example X

Grade 5 Grade 4,6 Roll-On

Beierdorf formula Grade 5 Grade 2,6