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Title:
ANILINE-DERIVATIVE-CONTAINING EXTERNAL AGENT FOR SKIN
Document Type and Number:
WIPO Patent Application WO/2023/214568
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an external agent for the skin. The agent contains an aniline derivative with a principle agent, and has a high active ingredient stability and percutaneous absorptivity. The present invention provides an external agent for the skin, the agent containing, as an active ingredient, a compound selected from the group consisting of an aniline derivative represented by formula (I) (where W represents S or O), a pharmaceutically acceptable salt thereof, or a hydrate of the same, the agent further containing a C16-20 monohydric higher alcohol or synthetic squalene.

Inventors:
YAMAGUCHI TETSUO (JP)
SAITO HANAE (JP)
AKIYAMA YUKA (JP)
AKASHI TAIKI (JP)
KURIMOTO SHOTA (JP)
Application Number:
PCT/JP2023/017077
Publication Date:
November 09, 2023
Filing Date:
May 01, 2023
Export Citation:
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Assignee:
KINOPHARMA INC (JP)
IWAKI SEIYAKU KK (JP)
International Classes:
A61K31/4545; A61K9/06; A61K47/06; A61K47/34; A61P17/00; A61P31/12; A61P31/22
Domestic Patent References:
WO2020218518A12020-10-29
Foreign References:
JP2020007274A2020-01-16
Other References:
AJIRO MASAHIKO, SAKAI HIROYUKI, ONOGI HIROSHI, YAMAMOTO MAKOTO, SUMI ERIKO, SAWADA TERUO, NOMURA TAKASHI, KABASHIMA KENJI, HOSOYA : "CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia", CLINICAL CANCER RESEARCH, ASSOCIATION FOR CANCER RESEARCH, US, vol. 24, no. 18, 15 September 2018 (2018-09-15), US, pages 4518 - 4528, XP055938710, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-17-3119
Attorney, Agent or Firm:
OSAWA Kenichi (JP)
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