Title:
ANIMAL MODEL EXPRESSING HUMAN CD3 AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/150763
Kind Code:
A1
Abstract:
The present invention relates to an animal model expressing human CD3 and a use thereof, and more specifically, to: an animal model into which a gene encoding human CD3 has been introduced; a method for producing the animal model; and a method for screening a therapeutic agent for T cell-mediated diseases using the animal model.
Inventors:
KIM SUN TAEK (KR)
RYU GI HYUCK (KR)
PARK SANG RAE (KR)
KWAK SEONG SUNG (KR)
JUNG HYUN HO (KR)
YANG GI HYEOK (KR)
RYU GI HYUCK (KR)
PARK SANG RAE (KR)
KWAK SEONG SUNG (KR)
JUNG HYUN HO (KR)
YANG GI HYEOK (KR)
Application Number:
PCT/KR2016/003358
Publication Date:
September 08, 2017
Filing Date:
March 31, 2016
Export Citation:
Assignee:
MEDYTOX INC (KR)
International Classes:
A01K67/027; C07K14/725; C12N15/85; G01N33/50
Foreign References:
| US20070209083A1 | 2007-09-06 | |||
| US5530179A | 1996-06-25 | |||
| EP2660250A1 | 2013-11-06 | |||
| CN105164153A | 2015-12-16 |
Other References:
KUHN, CHANTAL ET AL.: "Human CD 3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance", SCIENCE TRANSLATIONAL MEDICINE, vol. 3, no. 68, 2 February 2011 (2011-02-02), XP055249939
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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