Title:
ANIMAL MODEL WITH OBSESSIVE COMPULSIVE DISORDER USING NINJURIN 1 DEFICIENCY
Document Type and Number:
WIPO Patent Application WO/2015/023054
Kind Code:
A1
Abstract:
The present invention relates to an animal model with obsessive compulsive disorder, manufactured by deficiency of Ninjurin 1, and a method for searching candidate drugs for preventing or treating obsessive compulsive disorder using the same. According to the present invention, a Ninjurin 1 KO mouse can be provided as a new model for researching obsessive compulsive disorder, and memantine or a salt thereof, which is an NMDA receptor antagonist, can be provided as a new use for treating obsessive compulsive disorder
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Inventors:
KIM KYU-WON (KR)
LE HOANG (KR)
AHN BUM JU (KR)
OH GOO TAEG (KR)
JEON SEJIN (KR)
LE HOANG (KR)
AHN BUM JU (KR)
OH GOO TAEG (KR)
JEON SEJIN (KR)
Application Number:
PCT/KR2014/005531
Publication Date:
February 19, 2015
Filing Date:
June 23, 2014
Export Citation:
Assignee:
SNU R&DB FOUNDATION (KR)
UNIV EWHA IND COLLABORATION (KR)
UNIV EWHA IND COLLABORATION (KR)
International Classes:
A61K31/13; A61P25/00
Foreign References:
| KR20090029200A | 2009-03-20 |
Other References:
SEONG-JUN CHO ET AL.: "Ninjurinl, a target of p53, regulates p53 expression and p53- dependent cell survival, senescence, and radiation-induced mortality.", PROC NATL ACAD SCI U S A., vol. 110, no. 23, 4 June 2013 (2013-06-04), pages 9362 - 9367
Attorney, Agent or Firm:
ERUUM PATENT LAW FIRM (KR)
특허법인 이룸 (KR)
특허법인 이룸 (KR)
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