Title:
ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/081697
Kind Code:
A3
Abstract:
The present invention relates to novel anthelmintic compounds of formula (I) wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X1, X2, X3, X4, X5, X6, X7 and X8 are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.
Inventors:
MENG CHARLES Q (US)
LONG ALAN (US)
HUBER SCOT (US)
GURRALA SRINIVAS REDDY (US)
WILKINSON DOUGLAS EDWARD (US)
PACOFSKY GREGORY (US)
LONG ALAN (US)
HUBER SCOT (US)
GURRALA SRINIVAS REDDY (US)
WILKINSON DOUGLAS EDWARD (US)
PACOFSKY GREGORY (US)
Application Number:
PCT/US2013/070731
Publication Date:
September 25, 2014
Filing Date:
November 19, 2013
Export Citation:
Assignee:
MERIAL LTD (US)
International Classes:
C07D403/12; C07C205/06; C07D213/74; C07D215/38; C07D215/42; C07D217/06; C07D241/04; C07D263/58; C07D277/64; C07D333/66; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12
Domestic Patent References:
| WO2010115688A1 | 2010-10-14 | |||
| WO2009077527A1 | 2009-06-25 | |||
| WO2006014012A2 | 2006-02-09 |
Other References:
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DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719965, retrieved from STN Database accession no. 1058229-31-4
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DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719971, retrieved from STN Database accession no. 1058256-09-9
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719972, retrieved from STN Database accession no. 1058256-34-0
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DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719974, retrieved from STN Database accession no. 1058447-68-9
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719975, retrieved from STN Database accession no. 1060174-64-2
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719976, retrieved from STN Database accession no. 1060179-21-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719977, retrieved from STN Database accession no. 1060209-32-6
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DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719979, retrieved from STN Database accession no. 1278085-47-4
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719980, retrieved from STN Database accession no. 1293525-19-5
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719981, Database accession no. 1302832-45-6
SINGH J ET AL: "CHEMOTHERAPY OF FILARIASIS - ON THE SEARCH OF NEW AGENTS EFFECTIVE ON THE REPRODUCTIVE SYSTEM FEMALE ADULT WORMS", ZEITSCHRIFT FUER NATURFORSCHUNG. SECTION C. BIOSCIENCES,, vol. 45, no. 11/12, 1 January 1990 (1990-01-01), pages 1210 - 1214, XP001027282, ISSN: 0341-0382
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2007, XP002719957, retrieved from STN Database accession no. 924169-66-4
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2007, XP002719958, retrieved from STN Database accession no. 927571-60-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719959, retrieved from STN Database accession no. 1048639-02-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719960, retrieved from STN Database accession no. 1058200-26-2
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719961, retrieved from STN Database accession no. 1058204-48-0
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719962, retrieved from STN Database accession no. 1058204-80-0
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719963, retrieved from STN Database accession no. 1058228-61-7
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719964, retrieved from STN Database accession no. 1058228-86-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719965, retrieved from STN Database accession no. 1058229-31-4
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719966, retrieved from STN Database accession no. 1058234-57-3
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719967, retrieved from STN Database accession no. 1058234-68-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719968, retrieved from STN Database accession no. 1058236-89-7
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719969, retrieved from STN Database accession no. 1058237-30-1
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719970, retrieved from STN Database accession no. 1058256-03-3
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719971, retrieved from STN Database accession no. 1058256-09-9
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719972, retrieved from STN Database accession no. 1058256-34-0
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719973, retrieved from STN Database accession no. 1058447-24-7
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719974, retrieved from STN Database accession no. 1058447-68-9
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719975, retrieved from STN Database accession no. 1060174-64-2
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719976, retrieved from STN Database accession no. 1060179-21-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, XP002719977, retrieved from STN Database accession no. 1060209-32-6
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2009, XP002719978, retrieved from STN Database accession no. 1185021-40-2
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719979, retrieved from STN Database accession no. 1278085-47-4
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719980, retrieved from STN Database accession no. 1293525-19-5
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2011, XP002719981, Database accession no. 1302832-45-6
Attorney, Agent or Firm:
JARECKI-BLACK, Judy (3239 Satellite Blvd.Duluth, GA, US)
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