Title:
ANTI-AGING PHARMACEUTICAL COMPOSITION FOR MUSCLE CONTAINING AS ACTIVE INGREDIENT PARATHYROID HORMONE OR DERIVATIVE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/050160
Kind Code:
A1
Abstract:
The present invention provides an anti-aging pharmaceutical composition for muscle containing as the active ingredient parathyroid hormone, a parathyroid hormone derivative, or a salt thereof. Preferably the parathyroid hormone derivative is teriparatide. The anti-aging pharmaceutical composition is capable of preventing age-related reduction in muscular strength and preventing or treating sarcopenia and locomotive syndrome.
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Inventors:
HAGIHARA KEISUKE (JP)
Application Number:
PCT/JP2014/076289
Publication Date:
April 09, 2015
Filing Date:
October 01, 2014
Export Citation:
Assignee:
UNIV OSAKA (JP)
International Classes:
A61K38/22; A01K67/027; A61P21/00; C07K14/635; C12N15/09
Domestic Patent References:
| WO2005027915A1 | 2005-03-31 | |||
| WO2014162925A1 | 2014-10-09 |
Foreign References:
| JP2013519869A | 2013-05-30 |
Other References:
SHOTA KAGAWA ET AL.: "Goshajinkigan wa insulin/IGF1 Signal o Kaishite SAMP8 Mouse no Sarcopenia o Kaizen suru", J. TRADITIONAL MEDICINES, vol. 30, 29 July 2013 (2013-07-29), pages 62, O-10
MASAYUKI YAMAGUCHI ET AL.: "PTH no Kotsu Doka Sayo ni Okeru IGF-I/IRS-1 Signal no Kan'yo", THE JOURNAL OF THE JAPANESE ORTHOPAEDIC ASSOCIATION, vol. 78, no. 8, 2004, pages S1016
MASAYUKI YAMAGUCHI ET AL.: "Fuku Kojosen Hormone (PTH 1-34) no Kotsu Doka Sayo ni Okeru IGF-I/IRS-1 Signal no Kan'yo", THE ANNUAL MEETING OF THE JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH: PROGRAM & ABSTRACTS, vol. 22 ND, 2005, pages 204, P-068
KAJI, H. ET AL.: "Insulin-like growth factor-I mediates osteoclast-like cell formation stimulated by parathyroid hormone", J. CELL. PHYSIOL., vol. 172, no. 1, 1997, pages 55 - 62, XP002917107, DOI: doi:10.1002/(SICI)1097-4652(199707)172:1<55::AID-JCP6>3.0.CO;2-C
TAKESHI MIYAZAKI ET AL.: "Recent advances in basic and clinical research of osteoporosis", JAPANESE JOURNAL OF GERIATRICS, vol. 50, no. 2, 25 March 2013 (2013-03-25), pages 130 - 134
MASAYUKI YAMAGUCHI ET AL.: "PTH no Kotsu Doka Sayo ni Okeru IGF-I/IRS-1 Signal no Kan'yo", THE JOURNAL OF THE JAPANESE ORTHOPAEDIC ASSOCIATION, vol. 78, no. 8, 2004, pages S1016
MASAYUKI YAMAGUCHI ET AL.: "Fuku Kojosen Hormone (PTH 1-34) no Kotsu Doka Sayo ni Okeru IGF-I/IRS-1 Signal no Kan'yo", THE ANNUAL MEETING OF THE JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH: PROGRAM & ABSTRACTS, vol. 22 ND, 2005, pages 204, P-068
KAJI, H. ET AL.: "Insulin-like growth factor-I mediates osteoclast-like cell formation stimulated by parathyroid hormone", J. CELL. PHYSIOL., vol. 172, no. 1, 1997, pages 55 - 62, XP002917107, DOI: doi:10.1002/(SICI)1097-4652(199707)172:1<55::AID-JCP6>3.0.CO;2-C
TAKESHI MIYAZAKI ET AL.: "Recent advances in basic and clinical research of osteoporosis", JAPANESE JOURNAL OF GERIATRICS, vol. 50, no. 2, 25 March 2013 (2013-03-25), pages 130 - 134
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
Tatsu Iwatani (JP)
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