Title:
ANTI-AGING POTENTIAL OF EXTRACELLULAR METABOLITE ISOLATED FROM BACILLUS COAGULANS MTCC 5856
Document Type and Number:
WIPO Patent Application WO/2018/226556
Kind Code:
A3
Abstract:
Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-β, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.
Inventors:
MAJEED MUHAMMED (US)
NAGABHUSHANAM KALYANAM (US)
ARUMUGAM SIVAKUMAR
ALI FURQAN
MAJEED SHAHEEN (US)
MUNDKUR LAKSHMI
NAGABHUSHANAM KALYANAM (US)
ARUMUGAM SIVAKUMAR
ALI FURQAN
MAJEED SHAHEEN (US)
MUNDKUR LAKSHMI
Application Number:
PCT/US2018/035800
Publication Date:
January 17, 2019
Filing Date:
June 04, 2018
Export Citation:
Assignee:
MAJEED MUHAMMED (US)
NAGABHUSHANAM KALYANAM (US)
ARUMUGAM SIVAKUMAR (IN)
ALI FURQAN (IN)
MAJEED SHAHEEN (US)
MUNDKUR LAKSHMI (IN)
NAGABHUSHANAM KALYANAM (US)
ARUMUGAM SIVAKUMAR (IN)
ALI FURQAN (IN)
MAJEED SHAHEEN (US)
MUNDKUR LAKSHMI (IN)
International Classes:
A61K8/99; A01N63/02; C12N1/20
Foreign References:
| US20150044317A1 | 2015-02-12 | |||
| US20150173374A1 | 2015-06-25 |
Other References:
ICHIHASHI ET AL.: "Glycation stress and photo-aging in skin", ANTI-AGING MEDICINE, vol. 8, no. 3, 13 June 2011 (2011-06-13), pages 23 - 29, XP055573350
GARG ET AL.: "Molecular mechanisms of skin photoaging and plant inhibitors", INTERNATIONAL JOURNAL OF GREEN PHARMACY, vol. 11, no. 2, April 2017 (2017-04-01), pages 1 - 16, XP055573357
ALDAG ET AL.: "Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature", CLINICAL, COSMETIC AND INVESTIGATIONAL DERMATOLOGY, vol. 9, 9 November 2016 (2016-11-09), pages 411 - 419, XP055573360
GARG ET AL.: "Molecular mechanisms of skin photoaging and plant inhibitors", INTERNATIONAL JOURNAL OF GREEN PHARMACY, vol. 11, no. 2, April 2017 (2017-04-01), pages 1 - 16, XP055573357
ALDAG ET AL.: "Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature", CLINICAL, COSMETIC AND INVESTIGATIONAL DERMATOLOGY, vol. 9, 9 November 2016 (2016-11-09), pages 411 - 419, XP055573360
Attorney, Agent or Firm:
NAGABHUSHANAM, Kalyanam (US)
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