Title:
ANTI-CANCER AGENT COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2012/176823
Kind Code:
A1
Abstract:
Provided is an anti-cancer agent composition exhibiting excellent solubility and exerting high anti-cancer activity while exhibiting low toxicity. An anti-cancer composition characterized by containing a cyclodextrin compound and a phosphine transition metal complex represented by general formula (1). (In the formula, R1 and R2 represent a linear or branched alkyl group, a cycloalkyl group, a cycloalkyl group having a substituent, an adamantyl group, a phenyl group, or a phenyl group having a substituent, have a carbon number between 1 and 10, and may represent the same group or different groups. R3 and R4 represent a hydrogen atom or a linear or branched alkyl group, have a carbon number between 1 and 6, and may represent the same group or different groups. R3 and R4 may form a saturated or unsaturated ring by bonding to one another and said saturated or unsaturated ring may have a substituent. M represents a transition metal atom selected from among gold, copper, and silver. X- represents an anion.)
Inventors:
NAKATSUI KAZUHIRO (JP)
Application Number:
PCT/JP2012/065787
Publication Date:
December 27, 2012
Filing Date:
June 20, 2012
Export Citation:
Assignee:
NIPPON CHEMICAL IND (JP)
NAKATSUI KAZUHIRO (JP)
NAKATSUI KAZUHIRO (JP)
International Classes:
A61K31/675; A61K33/24; A61K47/40; A61P35/00; C07F1/08; C07F1/10; C07F1/12; C07F9/6509
Foreign References:
| JP2007320909A | 2007-12-13 |
Other References:
MITSURU HASHIDA: "Keiko Toyo Seizai no Sekkei to Hyoka", KABUSHIKI KAISHA YAKUGYO JIHOSHA, 1995, pages 184 - 185
Attorney, Agent or Firm:
NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP)
Nippon Chemical Industrial Co., Ltd. (JP)
Nippon Chemical Industrial Co., Ltd. (JP)
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Claims: