Title:
ANTI-CTLA4 MONOCLONAL ANTIBODY OR ANTIGEN BINDING FRAGMENT THEREOF, MEDICINAL COMPOSITION AND USE
Document Type and Number:
WIPO Patent Application WO/2016/015675
Kind Code:
A1
Abstract:
The present invention belongs to the fields of tumor treatment and molecular immunology and provides an anti-CTLA4 monoclonal antibody or an antigen binding fragment thereof, a medicinal composition thereof, and a use thereof. The monoclonal antibody of the present invention blocks CTLA4 from binding to B7, thereby eliminating the immunosuppressive effect of CTLA4 on the host and activating T lymphocytes.
Inventors:
LI BAIYONG (CN)
XIA YU (CN)
WANG ZHONGMIN (CN)
ZHANG PENG (CN)
PANG XINGHUA (CN)
XIA YU (CN)
WANG ZHONGMIN (CN)
ZHANG PENG (CN)
PANG XINGHUA (CN)
Application Number:
PCT/CN2015/085721
Publication Date:
February 04, 2016
Filing Date:
July 31, 2015
Export Citation:
Assignee:
AKESO BIOPHARMA INC (CN)
International Classes:
C07K16/28; A61K39/395; A61P35/00; A61P37/04; C07K19/00; C12N1/21; C12N5/10; C12N15/13; C12N15/63; G01N33/577
Foreign References:
CN103547595A | 2014-01-29 | |||
CN103221544A | 2013-07-24 | |||
CN101074264A | 2007-11-21 | |||
CN1328571A | 2001-12-26 |
Other References:
See also references of EP 3176181A4
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
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