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Title:
ANTI-ELTAS PROTEIN HUMANIZED ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/183700
Kind Code:
A1
Abstract:
Provided is an anti-eLtaS humanized antibody. The antibody comprises a heavy chain and a light chain both having a variable region and a constant region. The constant regions of both the heavy chain and the light chain come from a human body. An amino acid sequence of the variable region of the heavy chain is as represented by amino acids at positions 1-116 of SEQ ID NO:1, and an amino acid sequence of the variable region of the light chain is as represented by amino acids at positions 1-111 of SEQ ID NO:2. The humanized antibody can be used for resistance to staphylococcus aureus infection.

Inventors:
YANG GUANG (CN)
LIU YU (CN)
FENG JIANNAN (CN)
GAO YAPING (CN)
SHEN BEIFEN (CN)
Application Number:
PCT/CN2015/000504
Publication Date:
November 24, 2016
Filing Date:
July 14, 2015
Export Citation:
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Assignee:
BEIJING INST OF BASIC MEDICAL SCIENCES ACAD OF MILITARY MEDICAL SCIENCES (CN)
International Classes:
C07K16/40; A61K39/395; A61P31/04; C12N1/21; C12N5/10; C12N15/13; C12N15/63
Foreign References:
CN104861072A2015-08-26
CN103951749A2014-07-30
CN104558175A2015-04-29
Attorney, Agent or Firm:
JEEKAI & PARTNERS (CN)
北京纪凯知识产权代理有限公司 (CN)
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