Title:
ANTI-EPILEPTIC DRUG
Document Type and Number:
WIPO Patent Application WO/2014/203696
Kind Code:
A1
Abstract:
Provided is a novel anti-epileptic drug for the prevention and/or treatment of epileptic seizures that has a mode of action different from that of conventional anti-epileptic drugs. The anti-epileptic drug comprises as the active ingredient methylphenidate and/or a pharmaceutically acceptable salt thereof.
Inventors:
OUCHIDA MAMORU (JP)
OMORI IORI (JP)
OMORI IORI (JP)
Application Number:
PCT/JP2014/064120
Publication Date:
December 24, 2014
Filing Date:
May 28, 2014
Export Citation:
Assignee:
UNIV OKAYAMA NAT UNIV CORP (JP)
International Classes:
A61K31/4458; A61P25/08
Domestic Patent References:
| WO2001043730A2 | 2001-06-21 |
Foreign References:
| JPH11509226A | 1999-08-17 |
Other References:
KAZUHIRO YAMAKAWA: "7. Shikkan Tenkan: Na Channel Idenshi Hen'i to Yokuseikei Kino Shogai", MEDICAL SCIENCE, vol. 59, no. 5, 2008, pages 480 - 481
KAZUHIRO YAMAKAWA: "Tenkan no Kenkyu to Chiryo: Saikin no Shinpo Tenkan no Idenshi Kenkyu", THE JAPANESE JOURNAL OF PSYCHIATRY, vol. 11, no. 4, 2006, pages 355 - 361
IORI OMORI: "Tenkan Kanren Hen'igata Sodium Channel Nav1.1 ni Taisuru Ko Tenkan'yaku no Yakuri Koka", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 21, 2010, pages 43 - 48
TADAO SERIKAWA: "Sodium Channel Idenshi Scn1a Hen'i Rat no Kaihatsu Kaiseki Kenkyu", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 21, 2010, pages 29 - 36
MAMORU OUCHIDA: "Nyuji Jusho Myoclony Tenkan to sono Hen'en Tenkan Shokogun ni Okeru SCN1A Idenshi Ijo", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 18, 2007, pages 13 - 19
NINA BECHTEL ET AL.: "Attention-deficit/ hyperactivity disorder in childhood epilepsy: A neuropsychological and functional imaging study", EPILEPSIA, vol. 53, no. 2, 2012, pages 325 - 333
LOURIVAL BAPTISTA-NETO ET AL.: "An expert opinion on methylphenidate treatment for attention deficit hyperactivity disorder in pediatric patients with epilepsy", EXPERT OPIN. INVESTIG. DRUGS, vol. 17, no. 1, 2008, pages 77 - 84
KAZUHIRO YAMAKAWA: "Tenkan no Kenkyu to Chiryo: Saikin no Shinpo Tenkan no Idenshi Kenkyu", THE JAPANESE JOURNAL OF PSYCHIATRY, vol. 11, no. 4, 2006, pages 355 - 361
IORI OMORI: "Tenkan Kanren Hen'igata Sodium Channel Nav1.1 ni Taisuru Ko Tenkan'yaku no Yakuri Koka", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 21, 2010, pages 43 - 48
TADAO SERIKAWA: "Sodium Channel Idenshi Scn1a Hen'i Rat no Kaihatsu Kaiseki Kenkyu", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 21, 2010, pages 29 - 36
MAMORU OUCHIDA: "Nyuji Jusho Myoclony Tenkan to sono Hen'en Tenkan Shokogun ni Okeru SCN1A Idenshi Ijo", ANNUAL REPORT OF THE JAPAN EPILEPSY RESEARCH FOUNDATION, vol. 18, 2007, pages 13 - 19
NINA BECHTEL ET AL.: "Attention-deficit/ hyperactivity disorder in childhood epilepsy: A neuropsychological and functional imaging study", EPILEPSIA, vol. 53, no. 2, 2012, pages 325 - 333
LOURIVAL BAPTISTA-NETO ET AL.: "An expert opinion on methylphenidate treatment for attention deficit hyperactivity disorder in pediatric patients with epilepsy", EXPERT OPIN. INVESTIG. DRUGS, vol. 17, no. 1, 2008, pages 77 - 84
Attorney, Agent or Firm:
SHOJI, Takashi et al. (JP)
Takashi Shoji (JP)
Takashi Shoji (JP)
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