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Patent Searching and Data


Title:
ANTI-HIV DRUG
Document Type and Number:
WIPO Patent Application WO/1993/003035
Kind Code:
A1
Abstract:
An anti-HIV drug containing at least one porphyrin derivative selected between the following groups (A) and (B) as the active ingredient: (A) porphyrins modified with compounds selected among carbodiimides, alkylenediamines and alcohols, and (B) complexes between plasma proteins or chemically modified plasma proteins and porphyrins which may be modified with compounds selected among carbodiimides, alkylenediamines and alcohols. The drug is useful for preventing and treating AIDS, because it is excellent in the activity of killing HIV-infected cells, inhibiting cell injury caused by HIV infection and inhibiting HIV replication, and is highly safe.

Inventors:
MIZUMOTO KENJI (JP)
TSUBOI HIROSHI (JP)
MIYAJIMA HIDEKI (JP)
FUJIMOTO HIROSHI (JP)
AJISAKA KATSUMI (JP)
FUJIKI YUKIO (JP)
TSUNOO HAJIME (JP)
Application Number:
PCT/JP1992/000977
Publication Date:
February 18, 1993
Filing Date:
July 31, 1992
Export Citation:
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Assignee:
MEIJI MILK PROD CO LTD (JP)
International Classes:
A61K31/40; A61K31/555; A61K47/48; C07D487/22; C07K14/765; A61K38/00; (IPC1-7): A61K31/40; A61K31/555; A61K37/02; A61K39/395; C07D487/22; C07K15/12
Foreign References:
JPS63270627A1988-11-08
JPS63277700A1988-11-15
JPS63122622A1988-05-26
JPS62167783A1987-07-24
Other References:
See also references of EP 0601183A4
Attorney, Agent or Firm:
Aruga, Mitsuyuki (3-6 Nihonbashiningyo-cho 1-chom, Chuo-ku Tokyo 103, JP)
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