Title:
ANTI-INFLAMMATORY COMPOSITION COMPRISING MACROPIN PEPTIDE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/059711
Kind Code:
A1
Abstract:
The present invention relates to a functional health food composition and a pharmaceutical composition for preventing or ameliorating inflammatory diseases comprising a macropin peptide consisting of an amino acid sequence of SEQ ID NO: 1 as an active ingredient.
Inventors:
PARK YOONKYUNG (KR)
KO SU JIN (KR)
KO SU JIN (KR)
Application Number:
PCT/KR2018/011243
Publication Date:
March 28, 2019
Filing Date:
September 21, 2018
Export Citation:
Assignee:
UNIV CHOSUN IACF (KR)
International Classes:
A23L33/18; A61K8/64; A61K38/10; A61Q19/00
Domestic Patent References:
| WO2016143904A1 | 2016-09-15 |
Other References:
MONINCOVA, L. ET AL.: "Structure-activity study of macropin, a novel antimicrobial peptide from the venom of solitary bee Macropis fulvipes (Hymenoptera: Melittidae", JOURNAL OF PEPTIDE SCIENCE, vol. 20, no. 6, 11 March 2014 (2014-03-11), pages 375 - 384, XP055584763, ISSN: 1075-2617, DOI: 10.1002/psc.2625
AUFIERO, B.ET AL.: "Staphylococcus aureus induces the expression of tumor necrosis factor- a in primary human keratinocytes", INTERNATIONAL JOURNAL OF DERMATOLOGY, vol. 46, no. 7, 3 July 2007 (2007-07-03), pages 687 - 694, XP055584767
MONINCOVA, L.: "Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs", AMINO ACIDS ; THE FORUM FOR AMINO ACID AND PROTEIN RESEARCH, vol. 39, 3 March 2010 (2010-03-03) - 1 August 2010 (2010-08-01), pages 763 - 775, XP002600587, ISSN: 1438-2199, DOI: 10.1007/S00726-010-0519-1
NESUTA, 0.: "Antimicrobial peptide from the wild bee Hylaeus signatus venom and its analogues: structure-activity study and synergistic effect with antibiotics", JOURNAL OF NATURAL PRODUCTS, vol. 79, no. 4, 2016, pages 1073 - 1083, XP002758498, DOI: doi:10.1021/acs.jnatprod.5b01129
AUFIERO, B.ET AL.: "Staphylococcus aureus induces the expression of tumor necrosis factor- a in primary human keratinocytes", INTERNATIONAL JOURNAL OF DERMATOLOGY, vol. 46, no. 7, 3 July 2007 (2007-07-03), pages 687 - 694, XP055584767
MONINCOVA, L.: "Novel antimicrobial peptides from the venom of the eusocial bee Halictus sexcinctus (Hymenoptera: Halictidae) and their analogs", AMINO ACIDS ; THE FORUM FOR AMINO ACID AND PROTEIN RESEARCH, vol. 39, 3 March 2010 (2010-03-03) - 1 August 2010 (2010-08-01), pages 763 - 775, XP002600587, ISSN: 1438-2199, DOI: 10.1007/S00726-010-0519-1
NESUTA, 0.: "Antimicrobial peptide from the wild bee Hylaeus signatus venom and its analogues: structure-activity study and synergistic effect with antibiotics", JOURNAL OF NATURAL PRODUCTS, vol. 79, no. 4, 2016, pages 1073 - 1083, XP002758498, DOI: doi:10.1021/acs.jnatprod.5b01129
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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