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Title:
ANTI-INFLAMMATORY COMPOSITION AND METHOD FOR PRODUCTION OF ANTI-INFLAMMATORY COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2007/080962
Kind Code:
A1
Abstract:
[PROBLEMS] To discover an anti-inflammatory composition which comprises a casein digest or the like and has a higher activity. [MEANS FOR SOLVING PROBLEMS] Disclosed is an anti-inflammatory composition which is produced by subjecting a raw material such as a cheese or casein to lactic acid bacterium fermentation and/or enzymatic treatment. Preferably, a raw material such as a cheese or casein is fermented with a lactic acid bacterium belonging to the genus Lactococcus and then treated with two or more enzymes including a protease or a peptidase.

Inventors:
TONOUCHI HIDEKAZU (JP)
SASAKI HAJIME (JP)
KUME HISAE (JP)
TUCHIYA YOSHINOBU (JP)
Application Number:
PCT/JP2007/050317
Publication Date:
July 19, 2007
Filing Date:
January 12, 2007
Export Citation:
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Assignee:
MEIJI DAIRIES CORP (JP)
TONOUCHI HIDEKAZU (JP)
SASAKI HAJIME (JP)
KUME HISAE (JP)
TUCHIYA YOSHINOBU (JP)
International Classes:
A61K38/00; A23J3/34; A23L33/10; A23L33/17; A23L33/19; A61K35/20; A61K35/74; A61K38/01; A61K38/17; A61P1/16; A61P29/00; A61P37/06; A61P43/00
Foreign References:
JPH02300137A1990-12-12
JPS60224466A1985-11-08
US4600588A1986-07-15
JPH0641191A1994-02-15
JPH07278013A1995-10-24
JP2004002381A2004-01-08
JP2004155751A2004-06-03
Other References:
DADDAOUA A. ET AL: "Bovine glycomacropeptide is anti-inflammatory in rats with hapten-induced colitis", THE JOURNAL OF NUTRITION, vol. 135, no. 5, 2005, pages 1164 - 1170, XP003016084
KUME H. ET AL: "Nyusei Tanpakushitsu oyobi Nyusei Tanpakushitsu Trypsin Bunkai Peptide no ConA Yuhatsu Kan'en Hassho Yokusei Sayo", NIPPON BYOTAI EIYO GAKKAISHI, vol. 8, no. 1, 2005, pages 15 - 21, XP003016085
LAFFINEUR E. ET AL: "Immunomodulatory activity of beta-casein permeate medium fermented by lactic acid bacteria", JOURNAL OF DAIRY SCIENCE, vol. 79, no. 12, 1996, pages 2112 - 2120, XP001135053
TONOUCHI H. ET AL: "Concanavalin A Yuhatsu Kanshogai Model Mouse ni Okeru Kakushu Cheese no Koka", THE JAPANESE SOCIETY OF NUTRITION AND FOOD SCIENCE, vol. 60TH, April 2006 (2006-04-01), pages 267, XP003016086
HATORI M. ET AL: "Adjuvant Kansetsuen Rat ni Okeru Casein Koso Bunkaibutsu no Kansetsuen Yobo Koka", THE FOOD INDUSTRY, vol. 49, no. 16, July 2006 (2006-07-01), pages 71 - 72, XP003016087
Attorney, Agent or Firm:
SHIMURA, Hisashi (2-3-4 Minamisenba, Chuo-k, Osaka-shi Osaka 81, JP)
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