Title:
ANTI-INFLUENZA VIRUS AGENT, ANTI-RS VIRUS AGENT, AND ANTI-IMMUNODEFICIENCY VIRUS AGENT
Document Type and Number:
WIPO Patent Application WO/2010/005010
Kind Code:
A1
Abstract:
Disclosed are an anti-influenza virus agent, an anti-RS virus agent and an anti-immunodeficiency virus agent, each of which comprises a plant-derived component and has an excellent infection-preventing activity and an excellent proliferation-inhibiting activity against an influenza virus, an RS virus or an immunodeficiency virus, respectively. Each of the anti-influenza virus agent, the anti-RS virus agent and the anti-immunodeficiency virus agent is characterized by comprising an extract of a plant belonging to the family Betulaceae and/or a plant belonging to the family Meliaceae or a dried powder of leaves of the plant(s).
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Inventors:
NEROME KUNIAKI (JP)
Application Number:
PCT/JP2009/062405
Publication Date:
January 14, 2010
Filing Date:
July 08, 2009
Export Citation:
Assignee:
INST OF BIOLOG RESOURCES (JP)
NEROME KUNIAKI (JP)
NEROME KUNIAKI (JP)
International Classes:
A61K36/18; A61K36/00; A61P31/14; A61P31/16; A61P31/18
Domestic Patent References:
| WO2008001976A1 | 2008-01-03 | |||
| WO2008001968A1 | 2008-01-03 | |||
| WO2009075488A2 | 2009-06-18 |
Foreign References:
| JP2007254319A | 2007-10-04 |
Other References:
"Antiviral Activity of Panamanian Plant Extracts", PHYTOTHERAPY RESEARCH, vol. 6, no. 1, 1992, pages 38 - 43
KRASUTSKY, P.A. ET AL.: "Birch bark research and development", NAT PROD REP, vol. 23, no. 6, 2006, pages 919 - 42
KAIJ-A-KAMB, M. ET AL.: "Search for new antiviral agents of plant origin", PHARM ACTA HELV, vol. 67, no. 5-6, 1992, pages 130 - 47
MAY G. ET AL.: "Antiviral Activity of Aqueous Extracts from Medicinal Plants in Tissue Cultures", ARZNEIMITTEL FORSCHUNG, vol. 28, no. 1, 1978, pages 1 - 7
"HIV Protease Sogaizai o Mochiita Ko-HIV-yaku no Kenkyu, HIV Iyakuhinto Kaihatsu Kenkyu Hokoku", JAPAN HEALTH SCIENCES FOUNDATION, 1998, pages 37 - 44
"Biological Evaluation of Selected Plants from Poland", INTERNATIONAL JOURNAL OF PHARMACOGNOSY, vol. 35, no. 1, 1997, pages 1 - 5
YU, Y.B. ET AL.: "Effects of triterpenoids and flavonoids isolated from Alnus firma on HIV-1 viral enzymes", ARCH PHARM RES, vol. 30, no. 7, 2007, pages 820 - 6
"Solubilities of Betulin in Fourteen Organic Solvents at Different Temperatures", J. CHEM. ENG. DATA, vol. 52, no. 4, 2007, pages 1366 - 1368
"Inhibitory Effects of Various Edible Plants and Flavonoids from the Leaves of Cedrela sinensis on Human Immunodeficiency Virus Type 1 Protease", J. FOOD SCI. NUTR., vol. 5, no. 3, 2000, pages 170 - 173
"Screening of Some Indonesian Medicinal Plants for Inhibitory Effects on HIV-1 Protease", SHOYAKUGAKU ZASSHI, vol. 46, no. 2, 1992, pages 190 - 193
"Chlorogenic Acid, an HIV-1 Protease Inhibitor from Swietenia mahagoni L", PHYTOMEDICINE SUPPL, vol. 7, no. 2, 2000, pages 57
"HIV Protease Sogai Sayo o Yusuru Dento Yakubutsu no Tansaku", JOURNAL OF TRADITIONAL MEDICINES, vol. 11, no. 4, 1994, pages 416 - 417
"A Human Immunodeficiency Virus Protease Inhibitory Substance from Swietenia mahagoni", PHYTOTHERAPY RESEARCH, vol. 11, 1997, pages 433 - 436
KRASUTSKY, P.A. ET AL.: "Birch bark research and development", NAT PROD REP, vol. 23, no. 6, 2006, pages 919 - 42
KAIJ-A-KAMB, M. ET AL.: "Search for new antiviral agents of plant origin", PHARM ACTA HELV, vol. 67, no. 5-6, 1992, pages 130 - 47
MAY G. ET AL.: "Antiviral Activity of Aqueous Extracts from Medicinal Plants in Tissue Cultures", ARZNEIMITTEL FORSCHUNG, vol. 28, no. 1, 1978, pages 1 - 7
"HIV Protease Sogaizai o Mochiita Ko-HIV-yaku no Kenkyu, HIV Iyakuhinto Kaihatsu Kenkyu Hokoku", JAPAN HEALTH SCIENCES FOUNDATION, 1998, pages 37 - 44
"Biological Evaluation of Selected Plants from Poland", INTERNATIONAL JOURNAL OF PHARMACOGNOSY, vol. 35, no. 1, 1997, pages 1 - 5
YU, Y.B. ET AL.: "Effects of triterpenoids and flavonoids isolated from Alnus firma on HIV-1 viral enzymes", ARCH PHARM RES, vol. 30, no. 7, 2007, pages 820 - 6
"Solubilities of Betulin in Fourteen Organic Solvents at Different Temperatures", J. CHEM. ENG. DATA, vol. 52, no. 4, 2007, pages 1366 - 1368
"Inhibitory Effects of Various Edible Plants and Flavonoids from the Leaves of Cedrela sinensis on Human Immunodeficiency Virus Type 1 Protease", J. FOOD SCI. NUTR., vol. 5, no. 3, 2000, pages 170 - 173
"Screening of Some Indonesian Medicinal Plants for Inhibitory Effects on HIV-1 Protease", SHOYAKUGAKU ZASSHI, vol. 46, no. 2, 1992, pages 190 - 193
"Chlorogenic Acid, an HIV-1 Protease Inhibitor from Swietenia mahagoni L", PHYTOMEDICINE SUPPL, vol. 7, no. 2, 2000, pages 57
"HIV Protease Sogai Sayo o Yusuru Dento Yakubutsu no Tansaku", JOURNAL OF TRADITIONAL MEDICINES, vol. 11, no. 4, 1994, pages 416 - 417
"A Human Immunodeficiency Virus Protease Inhibitory Substance from Swietenia mahagoni", PHYTOTHERAPY RESEARCH, vol. 11, 1997, pages 433 - 436
Attorney, Agent or Firm:
KUMAKURA Yoshio et al. (JP)
Sadao Kumakura (JP)
Sadao Kumakura (JP)
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