Title:
ANTI-PARASITIC INFECTION EXTERNAL PHARMACEUTICAL FORMULATION, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/221862
Kind Code:
A1
Abstract:
Provided are an anti-parasitic infection external pharmaceutical formulation , a preparation method therefor and use thereof. The external pharmaceutical formulation comprises a first active ingredient and an aldehyde compound, the first active ingredient being an isoxazoline compound. The active ingredient aldehyde compound in the pharmaceutical formulation not only has insecticidal activity, but also can effectively improve the stability of the formulation. The transdermal rate of the external formulation is increased to improve the utilization rate of the pharmaceutically active ingredient.
Inventors:
ZHANG LIANG (CN)
LI SHOUJUN (CN)
LIU AILING (CN)
LI YALING (CN)
ZHANG PENGLI (CN)
LI YAN (CN)
ZHANG LINQI (CN)
LI SHOUJUN (CN)
LIU AILING (CN)
LI YALING (CN)
ZHANG PENGLI (CN)
LI YAN (CN)
ZHANG LINQI (CN)
Application Number:
PCT/CN2023/093563
Publication Date:
November 23, 2023
Filing Date:
May 11, 2023
Export Citation:
Assignee:
TIANJIN RINGPU BIO TECH CO LTD (CN)
RINGPU TIANJIN BIO PHARM CO LTD (CN)
RINGPU TIANJIN BIO PHARM CO LTD (CN)
International Classes:
A61K31/42; A61K31/11; A61P33/00; C07D261/04
Domestic Patent References:
| WO2007026965A1 | 2007-03-08 |
Foreign References:
| JP2020121955A | 2020-08-13 | |||
| JP2017061414A | 2017-03-30 | |||
| CN112493237A | 2021-03-16 |
Other References:
MA, XIAOHUI: "Research Progress of Traditional Chinese Medicine Transdermal Drug Delivery System", CHINA PRACTICAL MEDICINE, CN, vol. 10, no. 02, 20 January 2015 (2015-01-20), CN , pages 246 - 248, XP009550795, ISSN: 1673-7555, DOI: 10.14163/j.cnki.11-5547/r.2015.02.180
WU KE-NING; SHEN SHUI-BAO; WEI XIAO-FANG; YUAN RU-XI; LI XIU-YU; LEI LI-LI; ZHANG SHU-FANG; WU KE-WEN;: "Application and Research Progress of Cinnamaldehyde in Animal Husbandry", SILIAO YANJIU - FEED RESEARCH, SILIAO YANJIU ZAZHISHE, CN, no. 10, 31 December 2021 (2021-12-31), CN , pages 138 - 140, XP009550609, ISSN: 1002-2813
WU KE-NING; SHEN SHUI-BAO; WEI XIAO-FANG; YUAN RU-XI; LI XIU-YU; LEI LI-LI; ZHANG SHU-FANG; WU KE-WEN;: "Application and Research Progress of Cinnamaldehyde in Animal Husbandry", SILIAO YANJIU - FEED RESEARCH, SILIAO YANJIU ZAZHISHE, CN, no. 10, 31 December 2021 (2021-12-31), CN , pages 138 - 140, XP009550609, ISSN: 1002-2813
Attorney, Agent or Firm:
TIANJIN WISELY INTELLECTUAL PROPERTY AGENCY LTD. et al. (CN)
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