Title:
ANTI-PODOPLANIN ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2020/188836
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an anti-podoplanin antibody which is a humanized antibody or a mouse-human chimeric antibody, or an antibody fragment containing an antigen binding domain of the anti-podoplanin antibody. The problem can be solved by: an anti-podoplanin antibody which is an isolated humanized antibody or an isolated mouse-human chimeric antibody each comprising a specific amino acid sequence, or an antibody fragment containing an antigen binding domain of the antibody.
Inventors:
GYOBU NOBUHIKO (JP)
FUJITA NAOYA (JP)
KAKINO MAMORU (JP)
KAWASHIMA AI (JP)
FUJIHARA SHINYA (JP)
GODA NAOKI (JP)
FUJITA NAOYA (JP)
KAKINO MAMORU (JP)
KAWASHIMA AI (JP)
FUJIHARA SHINYA (JP)
GODA NAOKI (JP)
Application Number:
PCT/JP2019/023682
Publication Date:
September 24, 2020
Filing Date:
June 14, 2019
Export Citation:
Assignee:
JAPANESE FOUND FOR CANCER RES (JP)
API CO LTD (JP)
API CO LTD (JP)
International Classes:
C07K16/28; A61K39/395; A61P7/02; A61P35/00; A61P35/04; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; C12P21/08
Domestic Patent References:
| WO2017010463A1 | 2017-01-19 | |||
| WO2015053381A1 | 2015-04-16 | |||
| WO2017010463A1 | 2017-01-19 |
Other References:
TAKEMOTO,AI ET AL.: "Platelet-activating factor podoplanin:from discovery to drug development", CANCER METASTASIS REV, vol. 36, 2017, pages 225 - 234, XP036297597, ISSN: 0167-7659, DOI: 10.1007/s10555-017-9672-2
SEKIGUCHI, TAKAYA ET AL.: "Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis", ONCOTARGET, vol. 7, no. 4, 2015, pages 3934 - 3946, XP055345553, ISSN: 1949-2553, DOI: 10.18632/oncotarget.6598
J. CLIN. EXP. MED. (IGAKU NO AYUMI, vol. 265, no. 1, 2018, pages 60 - 65
JPN. J. THROMB. HEMOST., vol. 27, no. 1, 2016, pages 11 - 17
JPN. J. THROMB. HEMOST., vol. 28, no. 4, 2017, pages 518 - 526
#30. DEVELOPMENT OF HIGH-SENSITIVE ANTI-PODOPLANIN MABS AGAINST OSTEOSARCOMA, 21 January 2019 (2019-01-21), Retrieved from the Internet
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MONOCLON. ANTIB. IMMUNODIAGN. IMMUNOTHER., vol. 34, no. 3, June 2015 (2015-06-01), pages 154 - 61
BLOOD, vol. 129, no. 14, 6 April 2017 (2017-04-06), pages 1896 - 1898
J. BIOL. CHEM., vol. 278, no. 51, 19 December 2003 (2003-12-19), pages 51599 - 605
SEKIGUCHI, TAKAYA ET AL.: "Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis", ONCOTARGET, vol. 7, no. 4, 2015, pages 3934 - 3946, XP055345553, ISSN: 1949-2553, DOI: 10.18632/oncotarget.6598
J. CLIN. EXP. MED. (IGAKU NO AYUMI, vol. 265, no. 1, 2018, pages 60 - 65
JPN. J. THROMB. HEMOST., vol. 27, no. 1, 2016, pages 11 - 17
JPN. J. THROMB. HEMOST., vol. 28, no. 4, 2017, pages 518 - 526
#30. DEVELOPMENT OF HIGH-SENSITIVE ANTI-PODOPLANIN MABS AGAINST OSTEOSARCOMA, 21 January 2019 (2019-01-21), Retrieved from the Internet
HISTOPATHOLOGY, vol. 46, no. 4, April 2005 (2005-04-01), pages 396 - 402
HUM. PATHOL., vol. 36, no. 4, April 2005 (2005-04-01), pages 372 - 80
TUMOUR BIOL., vol. 26, no. 4, July 2005 (2005-07-01), pages 195 - 200
AM. J. PATHOL., vol. 166, no. 3, March 2005 (2005-03-01), pages 913 - 21
ACTA NEUROPATHOL., vol. 111, no. 5, May 2006 (2006-05-01), pages 483 - 8
CANCER CELL, vol. 9, no. 4, April 2006 (2006-04-01), pages 261 - 72
ACTA NEUROPATHOL., vol. 113, no. 1, January 2007 (2007-01-01), pages 87 - 94
INT. J. CANCER, vol. 134, no. 11, 1 June 2014 (2014-06-01), pages 2605 - 14
PATHOL. INT., vol. 60, no. 3, March 2010 (2010-03-01), pages 193 - 202
ONCOL. REP., vol. 25, no. 3, March 2011 (2011-03-01), pages 599 - 607
AM. J. PATHOL., vol. 179, no. 2, August 2011 (2011-08-01), pages 1041 - 9
MONOCLON. ANTIB. IMMUNODIAGN. IMMUNOTHER., vol. 34, no. 3, June 2015 (2015-06-01), pages 154 - 61
BLOOD, vol. 129, no. 14, 6 April 2017 (2017-04-06), pages 1896 - 1898
J. BIOL. CHEM., vol. 278, no. 51, 19 December 2003 (2003-12-19), pages 51599 - 605
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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