ANTI-PTK7 ANTIBODY, AND USE THEREOF

WIPO Patent Application WO/2024/054030

A1

The present invention relates to an anti-PTK7 antibody, and a use thereof. The anti-PTK7 antibody according to the present invention was found to exhibit the effect of inhibiting angiogenesis and the growth, migration, and infiltration of human umbilical vein endothelial cells (HUVECs) and may thus be used as a therapeutic agent for angiogenesis diseases and applied to various types of PTK7-positive cancer, and has the potential to be further developed as a target therapeutic agent for intractable cancers and used as a key global therapeutic agent for same. In addition, the antibody can be converted into a humanized antibody and used as an essential material for the development of novel drugs for clinical use, and can be used alone or in combination with drugs such as conventional anticancer drugs of proven effectiveness to maximize the effect of anticancer therapy.

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LEE SEUNG TAEK (KR)
SHIN WON SIK (KR)
OH SI WON (KR)
CHOI SO-YOUNG (KR)
LEE SE-RA (KR)
KIM SANG GIL (KR)

PCT/KR2023/013326

March 14, 2024

September 06, 2023

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UIF UNIV INDUSTRY FOUNDATION YONSEI UNIV (KR)
OSONG MEDICAL INNOVATION FOUND (KR)

C07K16/40; A61K39/00; A61P35/00

KR20220009910A	2022-01-25
KR20100101124A	2010-09-16
KR20170020753A	2017-02-24
US20100034826A1	2010-02-11
KR20210092236A	2021-07-23

ISIS IP LAW LLC (KR)

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