Title:
ANTI-RETROVIRAL DRUG
Document Type and Number:
WIPO Patent Application WO/1989/005141
Kind Code:
A1
Abstract:
An anti-retroviral drug containing an active ingredient comprising at least one member selected from the group consisting of ''syosaikoto'', baicalein, baicalin, quercetin, hesperetin, and alizarin represented by formula (I) (wherein R1, R2 and R3, which may be the same or different, each represents a hydrogen atom or a hydroxy group, and R4 represents a hydrogen atom, a sulfo group or a dicarboxymethylaminomethyl group), derivatives thereof and pharmacologically acceptable salts thereof. This drug is effective in treating human diseases induced by retrovirus.
Inventors:
ONO KATSUHIKO (JP)
FUKUSHIMA MASANORI (JP)
NAKANE HIDEO (JP)
NAKAGAMI SHIZUO (JP)
HIGUCHI HIROTAKA (JP)
MORI KAZUYA (JP)
SAKATA TOSHIYA (JP)
FUKUSHIMA MASANORI (JP)
NAKANE HIDEO (JP)
NAKAGAMI SHIZUO (JP)
HIGUCHI HIROTAKA (JP)
MORI KAZUYA (JP)
SAKATA TOSHIYA (JP)
Application Number:
PCT/JP1988/000919
Publication Date:
June 15, 1989
Filing Date:
September 12, 1988
Export Citation:
Assignee:
TSUMURA JUNTENDO KK (JP)
International Classes:
A61K31/12; A61K31/185; A61K31/19; A61K31/195; A61K31/205; A61K31/22; A61K31/35; A61K31/70; A61K36/00; A61K36/233; A61K36/258; A61K36/484; A61K36/489; A61K36/539; A61K36/725; A61K36/74; A61K36/8888; A61K36/9068; (IPC1-7): A61K31/12; A61K31/185; A61K31/195; A61K31/35; A61K31/70; A61K35/78
Foreign References:
| JPH05830642A |
Other References:
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YANO MICHIAKI (Rinsho Oyo Kanpo Shoho Kaisetsu) 20 July 1977 (20. 07. 77) Sogen-Sha, p. 263-p. 271
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See also references of EP 0348509A4
CHEMICAL ABSTRACTS, Vol. 102, No. 11, Abstract No. 92800m (CHEM. ABSTR. 102: 92800m) 18 March 1985 (18. 03. 85) (Columbus, Ohio, U.S.A.), T.N. KAUL, et. al., J. Med. Virol., 15, 71, (1985)
YANO MICHIAKI (Rinsho Oyo Kanpo Shoho Kaisetsu) 20 July 1977 (20. 07. 77) Sogen-Sha, p. 263-p. 271
CHEMICAL ABSTRACTS, Vol. 82, No. 13, Abstrct No. 80163m (CHEM. ABSTR. 82: 80163m) 31 March 1975 (31. 03. 75) (Columbus, Ohio, U.S.A.), A. KODA, Taisha 10, 730, (1973)
CHEMICAL ABSTRACTS, Vol. 96, No. 17, Abstract No. 137733t (CHEM. ABSTR. 96: 137733t), 26 April 1982 (26. 04. 82) (Columbus, Ohio, U.S.A.), Y. KIMURA, et. al., Chem. Pharm. Bull., 30, 219, (1982)
CHEMICAL ABSTRACTS, Vol. 101, No. 17, Abstract No. 143768w (CHEM. ABSTR. 101: 143768w), 22 October 1984 (22. 10. 84) (Columbus, Ohio, U.S.A.), M. KUBO, et. al., Chem. Pharm. Bull., 32, 2724, (1984)
CHEMICAL ABSTRACTS, Vol. 103, No. 15, Abstract No. 115972f (CHEM. ABSTR. 103: 115972f), 14 October 1985 (14. 10. 85) (Columbus, Ohio, U.S.A.), M. KUBO, et. al., Chem. Pharm. Bull., 33, 2411, (1985)
CHEMICAL ABSTRACTS, Vol. 76, No. 5, Abstract No. 21262w (CHEM. ABSTR. 76: 21262w) 31 January 1972 (31. 01. 72) (Columbus, Ohio, U.S.A.), A. KODA, et. al., Nippon Yakubutsugaku Zasshi, 66, 471, (1970)
CHEMICAL ABSTRACTS, Vol. 92, No. 20, Abstract No. 169246v (CHEM. ABSTR. 92: 169246v) 19 May 1980 (19. 05. 80) (Columbus, Ohio, U.S.A.), MADAUS, Dr., und Co., DE2, 826, 642 (1980)
CHEMICAL ABSTRACTS, Vol. 104, No. 23, Abstract No. 199515r (CHEM. ABSTR. 104: 199515r), 9 June 1986 (09. 06. 86) (Columbus, Ohio, U.S.A.), D. LORENZ, et. al., Methods. Find. Exp. Clin. Pharmacol., 7, 637, (1985)
CHEMICAL ABSTRACTS, Vol. 90, No. 8, Abstract No. 61242k (CHEM. ABSTR. 90: 61242k) 19 February 1979 (19. 02. 79) (Columbus, Ohio, U.S.A.), R.S. SCHREIBER, US, 4, 105, 758 (1978)
See also references of EP 0348509A4
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