Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ANTI-TIGIT ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS
Document Type and Number:
WIPO Patent Application WO/2019/129261
Kind Code:
A1
Abstract:
Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti- TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated by Tigit-mediated functions.

Inventors:
XUE, Liu (No.30 Science Park Road, Zhongguancun Life SciencePark, Changping District, Beijing 6, 102206, CN)
LIU, Qi (No.30 Science Park Road, Zhongguancun Life SciencePark, Changping District, Beijing 6, 102206, CN)
WEI, Min (No.30 Science Park Road, Zhongguancun Life SciencePark, Changping District, Beijing 6, 102206, CN)
LI, Kang (No.30 Science Park Road, Zhongguancun Life SciencePark, Changping District, Beijing 6, 102206, CN)
Application Number:
CN2018/125375
Publication Date:
July 04, 2019
Filing Date:
December 29, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
BEIGENE, LTD. (94 Solaris Avenue Camana Bay, Grand Cayman Cayman Islands, KY1-1108, GB)
ZHANG, Tong (No.30 Science Park Road, Zhongguancun Life Science Park Changping District, Beijing 6, 102206, CN)
International Classes:
A61K39/395; C07K14/47; C07K16/28
Domestic Patent References:
WO2016106302A92017-06-22
WO2017030823A22017-02-23
WO2016011264A12016-01-21
WO2016028656A12016-02-25
WO2015009856A22015-01-22
WO2016081746A22016-05-26
Attorney, Agent or Firm:
WU, FENG & ZHANG (3 FL, Building 2 Yard 3,,FengXiuZhongLu Road, Haidian District, Beijing 4, 100094, CN)
Download PDF: