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Patent Searching and Data


Title:
ANTI-TIGIT ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS
Document Type and Number:
WIPO Patent Application WO/2019/129261
Kind Code:
A1
Abstract:
Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti- TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated by Tigit-mediated functions.

Inventors:
XUE LIU (CN)
LIU QI (CN)
WEI MIN (CN)
LI KANG (CN)
Application Number:
CN2018/125375
Publication Date:
July 04, 2019
Filing Date:
December 29, 2018
Export Citation:
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Assignee:
BEIGENE LTD (GB)
ZHANG TONG (CN)
International Classes:
A61K39/395; C07K14/47; C07K16/28
Domestic Patent References:
WO2016106302A92017-06-22
WO2017030823A22017-02-23
WO2016011264A12016-01-21
WO2016028656A12016-02-25
WO2015009856A22015-01-22
WO2016081746A22016-05-26
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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