Title:
ANTIBACTERIAL COMBINATIONS COMPRISING POLYMYXIN
Document Type and Number:
WIPO Patent Application WO/2015/114452
Kind Code:
A3
Abstract:
The present disclosure relates to a novel combination of compounds, their use as antibacterials, compositions comprising them and methods for treating or preventing bacterial infections, more particularly, bacterial infections caused by Gram-negative pathogens and/or drug resistant Gram-negative bacteria.
Inventors:
COLLINS IAN (GB)
HAYDON DAVID JOHN (GB)
THOMAIDES-BREARS HELENA (GB)
PALMER JAMES T (AU)
LUNNISS CHRISTOPHER JAMES (AU)
HAYDON DAVID JOHN (GB)
THOMAIDES-BREARS HELENA (GB)
PALMER JAMES T (AU)
LUNNISS CHRISTOPHER JAMES (AU)
Application Number:
PCT/IB2015/000177
Publication Date:
November 12, 2015
Filing Date:
February 03, 2015
Export Citation:
Assignee:
BIOTA EUROPE LTD (GB)
International Classes:
A61K31/428; A61K45/06; A61P31/06
Domestic Patent References:
| WO2012177707A1 | 2012-12-27 | |||
| WO2013091011A1 | 2013-06-27 |
Foreign References:
| US20120184741A1 | 2012-07-19 | |||
| EP2018864A1 | 2009-01-28 | |||
| US20130252938A1 | 2013-09-26 |
Other References:
M. E. SOBIESZCZYK: "Combination therapy with polymyxin B for the treatment of multidrug-resistant Gram-negative respiratory tract infections", JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol. 54, no. 2, 1 July 2004 (2004-07-01), pages 566 - 569, XP055181729, DOI: 10.1093/jac/dkh369
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