Title:
ANTIBACTERIAL COMPOUNDS AGAINST DRUG RESISTANT BACTERIA
Document Type and Number:
WIPO Patent Application WO/2014/147578
Kind Code:
A3
Abstract:
The invention relates to the production of rifamycin analogs against drug resistant bacteria. The invention also relates to antibacterial compounds against drug resistant mycobacteria. The invention also provides for pharmaceutical composition comprising antibacterial compound against drug resistant bacteria, particularly mycobacteria. The invention also provides for use of antibacterial compounds for the treatment of disease caused by bacteria and in particular mycobacteria.
Inventors:
LAL RUP (IN)
MAHMUD TAIFO (US)
MAHMUD TAIFO (US)
Application Number:
PCT/IB2014/059989
Publication Date:
March 05, 2015
Filing Date:
March 20, 2014
Export Citation:
Assignee:
DEPT OF BIOTECHNOLOGY INDIA (IN)
UNIV DELHI (IN)
OREGON STATE (US)
UNIV DELHI (IN)
OREGON STATE (US)
International Classes:
A61K31/395; A61K31/4162; A61P31/04; A61P31/06; C07D498/00; C12N1/20; C12P17/18; C12R1/01
Other References:
"PROCEEDINGS OF THE NINETY NINTH SESSION OF THE INDIAN SCIENCE CONGRESS Bhubaneswar, 2012 PART II SECTION OF NEW BIOLOGY (Including Biochemistry, Biophysics & Molecular Biology and Biotechnology)", 2012, XP055131525, Retrieved from the Internet [retrieved on 20140724]
XU JUN ET AL: "Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699.", MICROBIOLOGY (READING, ENGLAND) AUG 2005, vol. 151, no. Pt 8, August 2005 (2005-08-01), pages 2515 - 2528, XP002727775, ISSN: 1350-0872
A. NIGAM ET AL: "Modification of Rifamycin Polyketide Backbone Leads to Improved Drug Activity Against Rifampicin-Resistant Mycobacterium tuberculosis", JOURNAL OF BIOLOGICAL CHEMISTRY, 12 June 2014 (2014-06-12), XP055131532, ISSN: 0021-9258, DOI: 10.1074/jbc.M114.572636
XU JUN ET AL: "Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699.", MICROBIOLOGY (READING, ENGLAND) AUG 2005, vol. 151, no. Pt 8, August 2005 (2005-08-01), pages 2515 - 2528, XP002727775, ISSN: 1350-0872
A. NIGAM ET AL: "Modification of Rifamycin Polyketide Backbone Leads to Improved Drug Activity Against Rifampicin-Resistant Mycobacterium tuberculosis", JOURNAL OF BIOLOGICAL CHEMISTRY, 12 June 2014 (2014-06-12), XP055131532, ISSN: 0021-9258, DOI: 10.1074/jbc.M114.572636
Attorney, Agent or Firm:
NAIR, Manisha Singh (Intellectual Property Practice709/710, Tolstoy House,15 - 17, Tolstoy Marg, New Delhi 1, IN)
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